Project description
A closer look at myopia crisis
Myopia, or near-sightedness, is becoming a global crisis, exacerbated by increasing education levels and evolving lifestyles among youth. By 2050, it’s anticipated that half of the world’s population will be myopic, posing a severe threat to future vision health. Complications stemming from myopia later in life are poised to escalate rates of blindness. Despite emerging prevention strategies, inadequate information and unpredictable outcomes hamper effective myopia control efforts by eye care professionals. In this context, the ERC-funded CONTROL-MYOPIA project will develop an agile, AI-driven clinical support system. By integrating multidisciplinary data, it aims to establish population-based norms, collect real-world evidence, identify non-responsive profiles, and predict outcomes using advanced machine learning. The CONTROL-MYOPIA platform promises tailored interventions.
Objective
Background:
Myopia, or near-sightedness, is increasing dramatically all over the world, mostly due to higher levels of education and changing lifestyles of young generations. The expectation is that half of the world’s citizens will be myopic by 2050. Myopia-related complications later in life are a serious threat to vision and will increase the rates of blindness. Prevention strategies and pharmacological and optical treatments to delay progression of myopia in childhood are emerging, but most eye care professionals still do not control myopia due to inadequate information and unpredictable outcomes.
Aim:
To radically improve patient management in myopia by providing an agile, AI-based clinical decision support system stooled on a solid scientific basis of integrated multidisciplinary data.
Approach:
1. To construct population-based reference centiles for eye growth and progression of myopia for screening and surveillance of myopia in young generations in Europe
2. To capture high-quality, long-term, prospective data from the real world on myopia control, and specifically gain evidence on timing, effectiveness, side effects, and acceptability of current treatment modalities in daily practice
3. To investigate patient profiles for poor response and adherence to myopia control
4. To predict the final outcome of myopia based on a plethora of potential predictors using advanced machine learning techniques
5. To develop the CONTROL-MYOPIA platform with a user-centred and highly interactive design which provides an accurate prediction of myopia outcomes with and without myopia control, and which recommends the right prevention and treatment for the right patient at the right time
Impact:
CONTROL-MYOPIA’s outcomes will have widespread impact on clinical care, patient participation, public health, design of clinical trials, research innovation, and policy changes
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2022-ADG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3015 GD Rotterdam
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.