3D spheroids derived from single cells for discovering stochastic patterns behind metastasis

Informations projet

3DSecret

N° de convention de subvention: 101099066

DOI

10.3030/101099066

Date de signature de la CE 16 Decembre 2022

Date de début 1 Janvier 2023

Date de fin 31 Decembre 2026

Financé au titre de

• The European Innovation Council (EIC)

Coût total

€ 2 591 050,25

Contribution de l’UE

€ 2 591 050,25

Coordonné par

INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY
Portugal

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Data Management Plan (1)

Data Management Plan

The DMP will provide an analysis of the main elements of the data management policy that will be used by the applications concerning all the datasets that will be generated by the project. The DMP is not a fixed document but evolves (if necessary) during the lifespan of the project, according to the Guidelines on Data Management.

Documents, reports (4)

Report of the selection of SERS substrates and strategy chosen for online metabolomics analysis.

A report compiling the results related to SERS performance for metabolomic sensing in droplets, selection of nanostructure composition, size and shape; preliminary results of integration in the microdroplets platform and identification of next steps for continuous monitoring without compromising SERS performance, cells viability and droplet stability.

Report for efficiency of traceable spheroid recovery from microfluidic devices.

A report compiling the results and selected final SOP for recovering spheroids from the growth platform, attained efficiencies and strategy for traceability for enabling subsequent genomic and transcriptomic analysis.

Plan for Dissemination and Exploitation Including Communication Activities

This plan provides a strategy and action plan concerning the communication and dissemination activities, channels, and target audience, project branding and KPIs/milestones. The deliverable also compiles the activities performed to grow the ecosystem and key stakeholders’ participation.

Website and logo

Project website and project logo information with also social media links.

Publications

Peer reviewed articles (5)

Will data analytics revolution finally bring SERS to the clinic?

Auteurs: A Mahmoud, A Teixeira, M Aranda, M Relvas, S Quintero, M Sousa-Silva, A Chícharo, M Chen, M Hashemi, J King, J Tunnell, C Morasso, F Piccotti, F Corsi, M Henriksen-Lacey, D de Aberasturi, D Méndez-Merino, A Rodríguez-Patón, Sara Abalde-Cela, L Dieguez
Publié dans: TrAC Trends in Analytical Chemistry, Numéro Volume 169, 117311, 2023, ISSN 0165-9936
Éditeur: Elsevier BV
DOI: 10.1016/j.trac.2023.117311

Intraline genomic heterogeneity of the triple-negative breast cancer MDA-MB-231-luc-GFP cell line

Auteurs: Nair Varela-Rouco, Nuria Estévez-Gómez, Cristóbal Fernández-Santiago, Laura Tomás, Miriam Pérez, Daniel García-Souto, Juan Jose Pasantes, Roberto Piñeiro, Joao M Alves, David Posada
Publié dans: Computational and Structural Biotechnology Journal, Numéro 27, 2025, ISSN 2001-0370
Éditeur: Elsevier BV
DOI: 10.1016/J.CSBJ.2025.06.033

Precision‐Engineered Plasmonic Nanostar Arrays for High‐Performance SERS Sensing

Auteurs: Alexandre Chícharo, Alexandra Teixeira, Diogo Moreira, Maria S. Relvas, Marta Aranda, Temple Douglas, Jerôme Borme, Jana B. Nieder, Lorena Diéguez, Sara Abalde‐Cela
Publié dans: Advanced Optical Materials, 2025, ISSN 2195-1071
Éditeur: Wiley
DOI: 10.1002/ADOM.202501275

Plasmonic nanoparticle sensors: current progress, challenges, and future prospects

Auteurs: Krishna Kant; Reshma Beeram; Yi Cao; Paulo S. S. dos Santos; Lara González-Cabaleiro; Daniel García-Lojo; Heng Guo; Younju Joung; Siddhant Kothadiya; Marta Lafuente; Yong Xiang Leong; Yiyi Liu; Yuxiong Liu; Sree Satya Bharati Moram; Sanje Mahasivam; Sonia Maniappan; Daniel Quesada-González; Divakar Raj; Pabudi Weerathunge; Xinyue Xia; Qian Yu; Sara Abalde-Cela; Ramon A. Alvarez-Puebla; Rizia Bardhan; Vipul Bansal; Jaebum Choo; Luis C. C. Coelho; José M. M. M. de Almeida; Sergio Gómez-Graña; Marek Grzelczak; Pablo Herves; Jatish Kumar; Theobald Lohmueller; Arben Merkoçi; José Luis Montaño-Priede; Xing Yi Ling; Reyes Mallada; Jorge Pérez-Juste; María P. Pina; Srikanth Singamaneni; Venugopal Rao Soma; Mengtao Sun; Limei Tian; Jianfang Wang; Lakshminarayana Polavarapu; Isabel Pastoriza Santos
Publié dans: Nanoscale Horizons, 2024, ISSN 2055-6764
Éditeur: RSC Publishing
DOI: 10.1039/D4NH00226A

Advanced Microfluidics for Single Cell‐Based Cancer Research

Auteurs: Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier
Publié dans: Advanced Science, 2025, ISSN 2198-3844
Éditeur: Wiley
DOI: 10.1002/ADVS.202500975