3D spheroids derived from single cells for discovering stochastic patterns behind metastasis

Informazioni relative al progetto

3DSecret

ID dell’accordo di sovvenzione: 101099066

DOI

10.3030/101099066

Data della firma CE 16 Dicembre 2022

Data di avvio 1 Gennaio 2023

Data di completamento 31 Dicembre 2026

Finanziato da

• The European Innovation Council (EIC)

Costo totale

€ 2 591 050,25

Contributo UE

€ 2 591 050,25

Coordinato da

INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY
Portugal

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Data Management Plan (1)

Data Management Plan

The DMP will provide an analysis of the main elements of the data management policy that will be used by the applications concerning all the datasets that will be generated by the project. The DMP is not a fixed document but evolves (if necessary) during the lifespan of the project, according to the Guidelines on Data Management.

Documents, reports (4)

Report of the selection of SERS substrates and strategy chosen for online metabolomics analysis.

A report compiling the results related to SERS performance for metabolomic sensing in droplets, selection of nanostructure composition, size and shape; preliminary results of integration in the microdroplets platform and identification of next steps for continuous monitoring without compromising SERS performance, cells viability and droplet stability.

Report for efficiency of traceable spheroid recovery from microfluidic devices.

A report compiling the results and selected final SOP for recovering spheroids from the growth platform, attained efficiencies and strategy for traceability for enabling subsequent genomic and transcriptomic analysis.

Plan for Dissemination and Exploitation Including Communication Activities

This plan provides a strategy and action plan concerning the communication and dissemination activities, channels, and target audience, project branding and KPIs/milestones. The deliverable also compiles the activities performed to grow the ecosystem and key stakeholders’ participation.

Website and logo

Project website and project logo information with also social media links.

Pubblicazioni

Peer reviewed articles (5)

Will data analytics revolution finally bring SERS to the clinic?

Autori: A Mahmoud, A Teixeira, M Aranda, M Relvas, S Quintero, M Sousa-Silva, A Chícharo, M Chen, M Hashemi, J King, J Tunnell, C Morasso, F Piccotti, F Corsi, M Henriksen-Lacey, D de Aberasturi, D Méndez-Merino, A Rodríguez-Patón, Sara Abalde-Cela, L Dieguez
Pubblicato in: TrAC Trends in Analytical Chemistry, Numero Volume 169, 117311, 2023, ISSN 0165-9936
Editore: Elsevier BV
DOI: 10.1016/j.trac.2023.117311

Intraline genomic heterogeneity of the triple-negative breast cancer MDA-MB-231-luc-GFP cell line

Autori: Nair Varela-Rouco, Nuria Estévez-Gómez, Cristóbal Fernández-Santiago, Laura Tomás, Miriam Pérez, Daniel García-Souto, Juan Jose Pasantes, Roberto Piñeiro, Joao M Alves, David Posada
Pubblicato in: Computational and Structural Biotechnology Journal, Numero 27, 2025, ISSN 2001-0370
Editore: Elsevier BV
DOI: 10.1016/J.CSBJ.2025.06.033

Precision‐Engineered Plasmonic Nanostar Arrays for High‐Performance SERS Sensing

Autori: Alexandre Chícharo, Alexandra Teixeira, Diogo Moreira, Maria S. Relvas, Marta Aranda, Temple Douglas, Jerôme Borme, Jana B. Nieder, Lorena Diéguez, Sara Abalde‐Cela
Pubblicato in: Advanced Optical Materials, 2025, ISSN 2195-1071
Editore: Wiley
DOI: 10.1002/ADOM.202501275

Plasmonic nanoparticle sensors: current progress, challenges, and future prospects

Autori: Krishna Kant; Reshma Beeram; Yi Cao; Paulo S. S. dos Santos; Lara González-Cabaleiro; Daniel García-Lojo; Heng Guo; Younju Joung; Siddhant Kothadiya; Marta Lafuente; Yong Xiang Leong; Yiyi Liu; Yuxiong Liu; Sree Satya Bharati Moram; Sanje Mahasivam; Sonia Maniappan; Daniel Quesada-González; Divakar Raj; Pabudi Weerathunge; Xinyue Xia; Qian Yu; Sara Abalde-Cela; Ramon A. Alvarez-Puebla; Rizia Bardhan; Vipul Bansal; Jaebum Choo; Luis C. C. Coelho; José M. M. M. de Almeida; Sergio Gómez-Graña; Marek Grzelczak; Pablo Herves; Jatish Kumar; Theobald Lohmueller; Arben Merkoçi; José Luis Montaño-Priede; Xing Yi Ling; Reyes Mallada; Jorge Pérez-Juste; María P. Pina; Srikanth Singamaneni; Venugopal Rao Soma; Mengtao Sun; Limei Tian; Jianfang Wang; Lakshminarayana Polavarapu; Isabel Pastoriza Santos
Pubblicato in: Nanoscale Horizons, 2024, ISSN 2055-6764
Editore: RSC Publishing
DOI: 10.1039/D4NH00226A

Advanced Microfluidics for Single Cell‐Based Cancer Research

Autori: Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier
Pubblicato in: Advanced Science, 2025, ISSN 2198-3844
Editore: Wiley
DOI: 10.1002/ADVS.202500975