Project description
Novel neural electrode arrays interfacing with peripheral nerve
Peripheral nerve interfaces sending signals between the human body and a machine processor aid in the restoration of function following disease or injury. The EU-funded BioFINE project plans to develop electrode arrays that can interface with peripheral nerves. Focus will be placed on addressing biocompatibility issues associated with long-term tissue integration and stability. Fine-tuned bioactivity will safeguard the surrounding neural tissue in the initial stages of healing, and implants of sub-cellular dimensions and tissue-compatible biomechanics approaches will safeguard tissue health. The proposed approach will offer the optimal conditions to bridge the gap from electrode to neuron and generate a long-term functional peripheral nerve interface.
Objective
BioFunctional IntraNeural Electrodes : In BioFINE we will develop flexible intraneural multielectrode arrays, capable of interfacing peripheral nerves e.g. to transfer input/output signals from bionic limbs. Specifically, we address the challenge of long term tissue integration and chronic stability, by addressing three aspects of biocompatibility: 1) We develop novel fabrication methods allowing the intraneural interface to be defined at even finer resolution than before; 2) we explore functionalizations which will control the tissue response by combined surface anchored and surface eluted agents; 3) we address structural biocompatibility on a system level by engineering novel implantable interconnects which reduced tethering forces and improve prospects for high channel count interfaces. Fine-tuned bioactivity will safe-guard surrounding neural tissue in the initial stages of healing, and implants of sub-cellular dimensions and tissue compatible biomechanics, will safe-guard tissue healthy in the longer term. The combined approach will offer optimal conditions to bridge the gap from electrode to neuron and generate a long term functional peripheral nerve interface. Indeed, each of the three technological advancements would on their own have substantial impact on neurotechnology, reaching far beyond intraneural interfaces.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been validated by the project's team.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2022-PATHFINDEROPEN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
412 96 GOTEBORG
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.