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ONCODIR – Evidence-based Participatory Decision Making for Cancer Prevention through implementation research

Project description

AI-driven solutions for colorectal cancer prevention

Unhealthy lifestyles and socioeconomic inequalities contribute to a rising burden of colorectal cancer (CRC), one of the most prevalent and deadly cancers. Prevention strategies exist, but they often fail to reach those most at risk due to behavioural, financial, and systemic barriers. Effective, personalised prevention requires a deeper understanding of lifestyle, economic, and cultural factors that influence health. Innovative, data-driven solutions are essential to improve early detection and prevention efforts. In this context, the EU-funded ONCODIR project brings together AI-powered analytics, health policy research, and social sciences to develop tailored CRC prevention strategies. Through large-scale pilot studies and citizen-driven design workshops, ONCODIR aims to create cost-effective, personalised, and trustworthy interventions that could transform cancer prevention in Europe.

Objective

Colorectal cancer (CRC) is one of the most common cancer types and its increased occurrence may be attributable to adverse health behaviors, especially in lower socioeconomic status populations. Stemming from the specific risk factors identified with CRC, ONCODIR integrates multidisciplinary research methods from health policy analytics; social and behavioural science; AI-powered multi-omics and retrospective data analytics as well as decision support theories to deliver evidence-based cancer prevention programmes and innovative AI-powered personalised prevention approaches. ONCODIR recognises that the evaluation of the ONCODIR prevention programmes needs to address cost effectiveness, affordability and cost benefit parameters. Thus it will also investigate cost balancing and demand generating financial schemes that will lead to enhanced CRC prevention programmes. The coherent technological ecosystem that ONCODIR is developing is based on robust AI trustworthiness and privacy preserving principles to deploy recommendation services that will be specified by citizens, health policy actors and SSH experts, during three design thinking workshops. SSH research will address aspects such as the life-status, nutritional and social habits in tandem with Economics, Sociology and Local/Regional Cultural identity and Ethics. ONCODIR’s results will be validated in three Laboratory Integration Tests (LITs) and three Large-scale Intervention Pilots (LIPs) in five EU member states, with the active involvement of medical scientists, health care providers, foundations and consortium experts. The ONCODIR consortium is composed of complementary partners, coming from multidisciplinary research, technological and SSH domains, with a proven track record of high-quality research capacity. The carefully structured workplan, embodies a holistic approach toward meeting the ONCODIR objectives and delivering feasible policy-supporting outcomes of significant exploitation potential. This action is part of the Cancer Mission cluster of projects on ‘Prevention and early detection.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-RIA - HORIZON Research and Innovation Actions

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MISS-2022-CANCER-01

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Coordinator

ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 905 000,00
Address
CHARILAOU THERMI ROAD 6 KM
57 001 THERMI THESSALONIKI
Greece

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Region
Βόρεια Ελλάδα Κεντρική Μακεδονία Θεσσαλονίκη
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 905 000,00

Participants (28)

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