Expand Flow – Accessing new chemical space via a combined flash- and photochemical flow chemistry approach for the functionalisation and ring expansion of heterocycles

Información del proyecto

Expand Flow

Identificador del acuerdo de subvención: 101106497

DOI

10.3030/101106497

Proyecto cerrado

Fecha de la firma de la CE 30 Marzo 2023

Fecha de inicio 16 Octubre 2023

Fecha de finalización 15 Octubre 2025

Financiado con arreglo a

• Marie Skłodowska-Curie Actions (MSCA)

Coste total

Sin datos

Aportación de la UE

€ 172 750,08

Coordinado por

UNIVERSITA DEGLI STUDI DI BARI ALDO MORO
Italy

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (1)

Communication, Dissemination & Exploitation Plan

The plan describes the planned measures to maximize the impact of the project, including the dissemination and exploitation measures that are planned, and the target group(s) addressed. Regarding communication measures and public engagement strategy, the aim is to inform and reach out to society and show the activities performed, and the use and the benefits the project will have for citizens.

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cycle for all data sets that will be collected, processed or generated by the action. It is a document describing what data will be collected, processed or generated and following what methodology and standards, whether and how this data will be shared and/or made open, and how it will be curated and preserved.

Publicaciones

Peer reviewed articles (9)

Generation and Use of Cyclopropenyllithium under Continuous Flow Conditions

Autores: Francesco Soddu, Iktedar Mahdi, Maria Chiara Cabua, Francesco Secci, Philipp Natho, Riccardo Tassoni, Paolo Dambruoso, Ernesto Mesto, Marco Colella, Renzo Luisi
Publicado en: Organic Letters, Edición 27, 2025, ISSN 1523-7060
Editor: American Chemical Society (ACS)
DOI: 10.5281/ZENODO.15542591

Continuous Flow Decarboxylative Monofluoroalkylation Enabled by Photoredox Catalysis

Autores: Francesco Pasca, Yuri Gelato, Michael Andresini, Defne Serbetci, Philipp Natho, Giuseppe Romanazzi, Leonardo Degennaro, Marco Colella, Renzo Luisi
Publicado en: JACS Au, Edición 5, 2025, ISSN 2691-3704
Editor: American Chemical Society (ACS)
DOI: 10.5281/ZENODO.14441184

Synthesis of Aza‐S(VI) Fluorides and Primary Sulfonimidamides from Sulfinylamines

Autores: Michael Andresini, Laura Marraffa, Defne Şerbetçi, Philipp Natho, Marco Colella, Leonardo Degennaro, Renzo Luisi
Publicado en: Advanced Synthesis & Catalysis, Edición 367, 2025, ISSN 1615-4150
Editor: Wiley
DOI: 10.5281/ZENODO.13957138

Azabicyclo[1.1.0]butyl‐Substituted Sulfonimidoyl Fluoride: Electrophilic Hub Bridging Late‐Stage Azetidine Incorporation with Sufex Chemistry

Autores: Defne Serbetci, Philipp Natho, Ernesto Mesto, Emanuela Schingaro, Marco Colella, Renzo Luisi
Publicado en: Advanced Synthesis & Catalysis, Edición 367, 2025, ISSN 1615-4150
Editor: Wiley
DOI: 10.5281/ZENODO.17257058

Shifting Lithium Amide Reactivity to the Radical Domain: Regioselective Radical C−H Functionalization of 3‐Iodooxetane for the Synthesis of 1,5‐Dioxaspiro[2.3]hexanes

Autores: Philipp Natho, Marco Colella, Annarita Vicenti, Giuseppe Romanazzi, Faizan Ullah, Nadeem S. Sheikh, Andrew J. P. White, Francesco Pasca, Renzo Luisi
Publicado en: Angewandte Chemie International Edition, Edición 64, 2025, ISSN 1433-7851
Editor: Wiley
DOI: 10.5281/ZENODO.14754638

1‐Oxa‐2,6‐Diazaspiro[3.3]heptane as a New Potential Piperazine Bioisostere – Flow‐Assisted Preparation and Derivatisation by Strain‐Release of Azabicyclo[1.1.0]butanes

Autores: Elena Graziano, Philipp Natho, Michael Andresini, Fabrizio Mastrolorito, Iktedar Mahdi, Ernesto Mesto, Marco Colella, Leonardo Degennaro, Orazio Nicolotti, Renzo Luisi
Publicado en: Advanced Synthesis & Catalysis, Edición 366, 2025, ISSN 1615-4150
Editor: Wiley
DOI: 10.5281/ZENODO.13365887

Iodonitrene-Mediated Nitrogen Transfer to Alkenes for the Direct Synthesis of NH-Aziridines

Autores: Yuri Gelato, Laura Marraffa, Francesco Pasca, Philipp Natho, Giuseppe Romanazzi, Arianna Tota, Marco Colella, Renzo Luisi
Publicado en: Journal of the American Chemical Society, Edición 147, 2025, ISSN 0002-7863
Editor: American Chemical Society (ACS)
DOI: 10.5281/ZENODO.17257145

Towards greener-by-design fine chemicals. Part 1: synthetic frontiers

Autores: Theodore A. Gazis, Jonas Wuyts, Areti Moutsiou, Giulio Volpin, Mark J. Ford, Rodolfo I. Teixeira, Katherine M. P. Wheelhouse, Philipp Natho, Polona Žnidaršič-Plazl, Sonja Jost, Renzo Luisi, Brahim Benyahia, Bert U. W. Maes, Gianvito Vilé
Publicado en: Chemical Society Reviews, 2025, ISSN 0306-0012
Editor: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5CS00929D

Flow chemistry as green technology for the genesis and use of organometallic reagents in the synthesis of key building blocks and APIs – An update

Autores: Philipp Natho, Renzo Luisi
Publicado en: Tetrahedron Green Chem, Edición 2, 2025, ISSN 2773-2231
Editor: Elsevier BV
DOI: 10.1016/J.TGCHEM.2023.100015