Expand Flow – Accessing new chemical space via a combined flash- and photochemical flow chemistry approach for the functionalisation and ring expansion of heterocycles

Informazioni relative al progetto

Expand Flow

ID dell’accordo di sovvenzione: 101106497

DOI

10.3030/101106497

Progetto chiuso

Data della firma CE 30 Marzo 2023

Data di avvio 16 Ottobre 2023

Data di completamento 15 Ottobre 2025

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 172 750,08

Coordinato da

UNIVERSITA DEGLI STUDI DI BARI ALDO MORO
Italy

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I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (1)

Communication, Dissemination & Exploitation Plan

The plan describes the planned measures to maximize the impact of the project, including the dissemination and exploitation measures that are planned, and the target group(s) addressed. Regarding communication measures and public engagement strategy, the aim is to inform and reach out to society and show the activities performed, and the use and the benefits the project will have for citizens.

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cycle for all data sets that will be collected, processed or generated by the action. It is a document describing what data will be collected, processed or generated and following what methodology and standards, whether and how this data will be shared and/or made open, and how it will be curated and preserved.

Pubblicazioni

Peer reviewed articles (9)

Generation and Use of Cyclopropenyllithium under Continuous Flow Conditions

Autori: Francesco Soddu, Iktedar Mahdi, Maria Chiara Cabua, Francesco Secci, Philipp Natho, Riccardo Tassoni, Paolo Dambruoso, Ernesto Mesto, Marco Colella, Renzo Luisi
Pubblicato in: Organic Letters, Numero 27, 2025, ISSN 1523-7060
Editore: American Chemical Society (ACS)
DOI: 10.5281/ZENODO.15542591

Continuous Flow Decarboxylative Monofluoroalkylation Enabled by Photoredox Catalysis

Autori: Francesco Pasca, Yuri Gelato, Michael Andresini, Defne Serbetci, Philipp Natho, Giuseppe Romanazzi, Leonardo Degennaro, Marco Colella, Renzo Luisi
Pubblicato in: JACS Au, Numero 5, 2025, ISSN 2691-3704
Editore: American Chemical Society (ACS)
DOI: 10.5281/ZENODO.14441184

Synthesis of Aza‐S(VI) Fluorides and Primary Sulfonimidamides from Sulfinylamines

Autori: Michael Andresini, Laura Marraffa, Defne Şerbetçi, Philipp Natho, Marco Colella, Leonardo Degennaro, Renzo Luisi
Pubblicato in: Advanced Synthesis & Catalysis, Numero 367, 2025, ISSN 1615-4150
Editore: Wiley
DOI: 10.5281/ZENODO.13957138

Azabicyclo[1.1.0]butyl‐Substituted Sulfonimidoyl Fluoride: Electrophilic Hub Bridging Late‐Stage Azetidine Incorporation with Sufex Chemistry

Autori: Defne Serbetci, Philipp Natho, Ernesto Mesto, Emanuela Schingaro, Marco Colella, Renzo Luisi
Pubblicato in: Advanced Synthesis & Catalysis, Numero 367, 2025, ISSN 1615-4150
Editore: Wiley
DOI: 10.5281/ZENODO.17257058

Shifting Lithium Amide Reactivity to the Radical Domain: Regioselective Radical C−H Functionalization of 3‐Iodooxetane for the Synthesis of 1,5‐Dioxaspiro[2.3]hexanes

Autori: Philipp Natho, Marco Colella, Annarita Vicenti, Giuseppe Romanazzi, Faizan Ullah, Nadeem S. Sheikh, Andrew J. P. White, Francesco Pasca, Renzo Luisi
Pubblicato in: Angewandte Chemie International Edition, Numero 64, 2025, ISSN 1433-7851
Editore: Wiley
DOI: 10.5281/ZENODO.14754638

1‐Oxa‐2,6‐Diazaspiro[3.3]heptane as a New Potential Piperazine Bioisostere – Flow‐Assisted Preparation and Derivatisation by Strain‐Release of Azabicyclo[1.1.0]butanes

Autori: Elena Graziano, Philipp Natho, Michael Andresini, Fabrizio Mastrolorito, Iktedar Mahdi, Ernesto Mesto, Marco Colella, Leonardo Degennaro, Orazio Nicolotti, Renzo Luisi
Pubblicato in: Advanced Synthesis & Catalysis, Numero 366, 2025, ISSN 1615-4150
Editore: Wiley
DOI: 10.5281/ZENODO.13365887

Iodonitrene-Mediated Nitrogen Transfer to Alkenes for the Direct Synthesis of NH-Aziridines

Autori: Yuri Gelato, Laura Marraffa, Francesco Pasca, Philipp Natho, Giuseppe Romanazzi, Arianna Tota, Marco Colella, Renzo Luisi
Pubblicato in: Journal of the American Chemical Society, Numero 147, 2025, ISSN 0002-7863
Editore: American Chemical Society (ACS)
DOI: 10.5281/ZENODO.17257145

Towards greener-by-design fine chemicals. Part 1: synthetic frontiers

Autori: Theodore A. Gazis, Jonas Wuyts, Areti Moutsiou, Giulio Volpin, Mark J. Ford, Rodolfo I. Teixeira, Katherine M. P. Wheelhouse, Philipp Natho, Polona Žnidaršič-Plazl, Sonja Jost, Renzo Luisi, Brahim Benyahia, Bert U. W. Maes, Gianvito Vilé
Pubblicato in: Chemical Society Reviews, 2025, ISSN 0306-0012
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5CS00929D

Flow chemistry as green technology for the genesis and use of organometallic reagents in the synthesis of key building blocks and APIs – An update

Autori: Philipp Natho, Renzo Luisi
Pubblicato in: Tetrahedron Green Chem, Numero 2, 2025, ISSN 2773-2231
Editore: Elsevier BV
DOI: 10.1016/J.TGCHEM.2023.100015