Objective
Current long-term archival media (such as tape and disk) have several issues, the most important one being that they are short lived (up to 5-10 years) forcing data to be copied between storage media every few years in a costly process which also produces considerable electronic waste.
Longer-lasting media are desperately needed and DNA oligos have been identified as a major contender to be the next archival storage medium. With it, data is written using DNA synthesis and read using DNA sequencing. DNA is particularly promising as a storage medium, due to its durability as it can last for several hundreds of years. However, storing data in DNA oligos is currently too expensive due to the exorbitant cost of DNA synthesis (~0.12USD to write one bit) as well as issues such as speed in writing (synthesis) and reading (sequencing).
For this reason, we propose to investigate storing data in DNA nanostructures. Our approach is based on producing DNA nanostructures, like a breadboard, and attaching streptavidin at a given set of locations, to either write a one if streptavidin is present or a zero otherwise. The major benefit of our approach is that all possible nanostructures can be built out of a predefined, small set of DNA oligos which can be produced cheaply and en-masse. Writing is therefore substantially cheaper. With our approach, writing, reading (based on atomic force microscopy), and editing are also substantially faster. Editing information is currently infeasible with DNA storage based on oligos.
We have successfully demonstrated the feasibility of both writing and reading in proof-of-concept experiments, giving confidence in the approach. The goal of this proposal is to scale up the basic but successfully tested idea to make this a feasible approach at a larger scale.
The team proposing this work is ideally placed to make the research a success. The team brings all the necessary expertise together.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences physical sciences optics microscopy
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC - HORIZON EIC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2022-PATHFINDERCHALLENGES-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
33098 Paderborn
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.