Next Generation Molecular Data Storage

Project Information

NEO

Grant agreement ID: 101115317

DOI

10.3030/101115317

EC signature date 2 June 2023

Start date 1 October 2023

End date 30 September 2026

Funded under

• The European Innovation Council (EIC)

Total cost

€ 2 418 514,98

EU contribution

€ 2 418 514,98

Coordinated by

UNIVERSITAET PADERBORN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (5)

Plan for Dissemination and Communication Activities

Define the Dissemination and Communication Plan

Website and project logo

Website and project logo information with also social media links

Demonstration of 6-way DNA strand displacement reactions

6-way DNA strand displacement reactions are demonstrated on DNA origami substrates. The speeds of 30 individual reactions are determined in solution and on surfaces in order to identify specific effects of surface immobilization.

Cost efficient folding of DNA nanostructures

An optimized protocol for low-cost folding of DNA origami nanostructures is developed that employs a minimum amount of staple strands in DNA origami assembly and enables the recycling of unincorporated staple strands after purification.

Basic characterisation of nanostructure using AFM

Reproducible imaging of molecular bumps embedded within the DNA origami nanostructures is demonstrated. Relatively non-invasive (soft) AFM imaging modes are employed in order maximize the resilience of the molecular bits to the repetitive reading process.

Data Management Plan (1)

Data Management plan

Define the Data Management Plan

Publications

Peer reviewed articles (5)

Stability of Information‐Carrying DNA Origami Nanostructures During Repeated Freeze–Thaw Cycles

Author(s): Xinyang Li, Lukas Rabbe, Jacqueline Linneweber, Guido Grundmeier, Adrian Keller
Published in: Chemistry–Methods, Issue 6, 2026, ISSN 2628-9725
Publisher: Wiley
DOI: 10.1002/CMTD.202500161

Cost-efficient folding of functionalized DNA origami nanostructures <i>via</i> staple recycling

Author(s): Emilia Tomm, Guido Grundmeier, Adrian Keller
Published in: Nanoscale, Issue 17, 2025, ISSN 2040-3364
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5NR01435B

CpG Methylation Protects DNA against Ionizing Radiation

Author(s): Leo Sala, Tereza Zápotocká, Jana Šáchová, Václav Olšanský, David Chvátil, François Chevalier, Violaine Vizcaino, Alain Méry, Jaroslav Kočišek
Published in: The Journal of Physical Chemistry B, Issue 129, 2025, ISSN 1520-6106
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACS.JPCB.5C04043

Toward high-density streptavidin arrays on DNA origami nanostructures

Author(s): Lukas Rabbe, Emilia Tomm, Guido Grundmeier, Adrian Keller
Published in: RSC Advances, Issue 15, 2025, ISSN 2046-2069
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5RA03393D

Breaking of the Up‐Down Symmetry of DNA Origami on a Solid Substrate

Author(s): Gangamallaiah Velpula, Emilia Tomm, Boxuan Shen, Kunal S. Mali, Adrian Keller, Steven De Feyter
Published in: Angewandte Chemie, Issue 137, 2025, ISSN 0044-8249
Publisher: Wiley
DOI: 10.1002/ANGE.202507613