Project description
Advancing Alzheimer’s research for a healthier future
Alzheimer’s disease and its tau-related counterparts encompass a spectrum of neurodegenerative disorders characterised by the accumulation of abnormal tau protein in the brain. These tauopathies include diseases like progressive supranuclear palsy, corticobasal degeneration and frontotemporal dementia, among others. The pressing need for efficient diagnostics and treatments is undeniable, given the immense burden these diseases place on individuals, families and society at large. In this context, the MSCA-funded TAME project unites leading academic and industry experts to enhance understanding of tau-related diseases and develop safer, personalised diagnostics and interventions. Specifically, the project’s multidisciplinary approach combines molecular neuroscience, computing, chemical and bio-engineering expertise. Through training nine talented life scientists, the project emphasises research, personal development and open science.
Objective
There is an urgent medical need for efficient diagnostics for Alzheimer’s disease and related tauopathies, as well as disease modifying treatments, due to the heavy burden of the disease on patients, families and society. To address this public health issue, TAME R&I training network gathers leading academic and industrial experts in tau research with the ambition to keep older people active and independent for longer. TAME aims to provide better understanding of tau-related diseases and supports the development of new, safer, personalised and more effective diagnosis and interventions for AD and the less common tauopathies. The beneficiaries and partners bring together resources and knowledge across different fields and technologies to provide a multidisciplinary approach necessary to take on the challenge. They have teamed-up to combine molecular and cellular neuroscience with computing, chemical and bio-engineering and their technology expertise. The first tau network of Europe, TAME, will focus on novel approaches using nanobodies, which have emerged as very promising antibody formats in tau research. The primary objective of the TAME is to train 9 fellows to deliver the next generation of talented life scientists. The program will be a combination of training in research, in personal and professional development and in open science, achieved by conducting research projects, attending courses and benefiting from internal mobility within TAME. The research training is based on cutting-edge technologies and advanced models for medical research, emphasizing the need for more human-based research, gender-personalised models and reduction in the use of animals. Consequently, through intense collaboration with all partners and the relevant industrial experience, these 9 fellows can anticipate improved career prospects and higher employability. TAME will provide an innovation-friendly framework in which scientific results can mature and be developed into products.
Fields of science
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral NetworksCoordinator
75794 Paris
France
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Participants (8)
12489 Berlin
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16672 Vari-Athens
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4000 Liege
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1081 HV Amsterdam
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405 30 Goeteborg
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28006 Madrid
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91000 Evry-Courcouronnes
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
27200 Vernon
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partners (13)
33270 Floirac
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
91190 Gif-Sur-Yvette
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53175 Bonn
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1170 Bruxelles / Brussel
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4430 Ans
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
106 Taipei
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
9052 Gent
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
08007 Barcelona
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1081 HV Amsterdam
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10561 Athina
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59000 Lille
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14195 +4930209346295
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75654 Paris
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