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Volatolomic approaches for improving success rates in assisted reproductive technology

Project description

Enhanced embryo assessment through volatile compounds

Volatolomics is an emerging field in medical research that focuses on analysing the volatile organic compounds (VOCs) emitted by the human body. These VOCs are small molecules that can be detected in breath, sweat, urine and other bodily fluids. The idea behind volatolomics is that changes in the composition or concentration of these VOCs could potentially serve as biomarkers for various health conditions. Funded by the Marie Skłodowska-Curie Actions programme, the ARTVOC project aims to take volatolomics a step further for non-invasively assessing the quality of embryos. The aim is to identify the most viable embryos for transfer and enhance success rates in in vitro fertilisation procedures.

Objective

Volatolomics has emerged as a new frontier in deciphering unreached matters related with health conditions. Volatolomics research is based on the study of the volatile compounds emitted by biological samples. It was demonstrated that the volatiles emitted though breath, skin, feces, urine or cells can provide useful information for the diagnosis of an important number of diseases, such as cancer, diabetes, or even neurodegenerative disorders. We have very recently demonstrated that the embryos do also emit volatiles during their development, while genetical disorders alter the pattern of the released volatiles. In the present project, we aim at assessing volatolomic techniques for the non-invasive assessment of embryos quality in order to select the most viable ones for transfer. The ultimate goal of this project is to achieve higher success rates in the in vitro fertilisation.

Fields of science (EuroSciVoc)

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Coordinator

EESTI MAAULIKOOL
Net EU contribution
€ 552 000,00
Address
KREUTZWALDI 1
51014 Tartu
Estonia

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Region
Eesti Eesti Lõuna-Eesti
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data

Participants (3)

Partners (4)