Project description
A greener and healthier future for both plant and human well-being
Agriculture’s sustainability challenges are reaching critical levels, calling for innovative eco-friendly solutions. Extracellular vesicles, tiny structures released by living cells, have long been known for their pivotal roles in cellular communication. Now, researchers are exploring plant-derived vesicles as a game-changing alternative to those from mammalian cells. With the support of Marie Skłodowska-Curie Actions, the FarmEVs project will harness plant-derived vesicles to revolutionise sustainable agriculture, creating a greener, healthier future for all. It will establish a large-scale, vegetable-based system for vesicle production by harnessing organically grown crops. These plant-derived vesicles are set to revolutionise sustainable agriculture, thanks to the collaborative efforts of an international consortium comprising eight partners from six countries.
Objective
Extracellular vesicles (EVs) are biomembrane-enclosed structures that are ubiquitously secreted by living cells. EVs, by transferring proteins, lipids, nucleic acids and other molecules to neighbouring or distant cells contribute to tissue homeostasis and have roles in many physiological and pathological processes. In this context, plant-derived vesicles started to receive attention as valid alternatives to EVs released by mammalian cell. Going beyond the state-of-the-art and relying on a highly interconnected approach, FarmEVs project will setup a vegetable-based system for the massive production of vesicles and explore them as high-value ingredients for plant and human health. This will be achieved through the isolation and engineerization of EV-like nanovesicles from organically grown crops. Plant derived-vesicles will be exploited for sustainable agriculture with the help of an organic farm in Finland and an agricultural university in Egypt. Moreover, we will setup plant cell cultures for EV farming and by applying emerging biotechnology we will develop EV-based solutions to increase the viral resistance of plants and the pro-symbiotic activities in legume crops.
To achieve the goals, a multidisciplinary consortium with the participation of 8 partners from universities, research centres, an SME and an organic farm from 6 countries has been created with the integration of a broad expertise ranging from EV research, biomembrane modelling, plant genetics, plant physiology, virology, molecular farming, engineering and agriculture. This project will strengthen the already existing collaborations, create new ones and provide a solid cornerstone for further research efforts of the consortium participants after the ending of the project. An ambitious staff exchange programme for the transfer of scientific and transferable skills, dissemination and outreach activities was implemented into the scientific plan.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology virology
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences biochemistry biomolecules lipids
- medical and health sciences basic medicine physiology homeostasis
- agricultural sciences agriculture, forestry, and fisheries agriculture grains and oilseeds legumes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff Exchanges
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-SE-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
00185 Roma
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.