Objective
Healthcare is the fasted growing EU27 expenditure. Personalised medicine, comprising tailored approaches for prevention, diagnosis, monitoring and treatment is essential to reduce the burden of disease and improve the quality of life. Integration of multiple data types (multimodal data) into artificial intelligence models is required for the development of accurate and personalised interventions. This is particularly true for the inclusion of genomic data, which is information-rich and individual-specific, and more routinely available as the cost of sequencing continues to fall. Multimodal data integration is complex due to privacy & governance requirements, the presence of multiple standards, distinct data formats, and underlying data complexity and volume. NextGen tools will remove barriers in data integration several cardiovascular use cases. NextGen deliverables will include tooling for multimodal data integration and research portability, extension of secure federated analytics to genomic computation, more effective federated learning over distributed infrastructures, more effective and accessible tools for genomic data analysis; improved clinical efficiency of variant prioritisation; scalable genomic data curation; and improved data discoverability and data management. A comprehensive gap analysis of the existing landscape, factoring ongoing initiatives will ensure NextGen deliverables are forward-looking and complementary. NextGen embedded governance framework and robust regulatory processes will ensure secure multi-jurisdictional multiomic multimodal data access aligned with initiatives including “1+ Million Genomes” and the European Health Data Space. Several real-world pilots will demonstrate the effectiveness of NextGen tools and will be integrated in the NextGen Pathfinder network of five collaborating clinical sites as a self-contained data ecosystem and comprehensive proof of concept.
Fields of science
Programme(s)
Funding Scheme
HORIZON-RIA - HORIZON Research and Innovation ActionsCoordinator
3584 CX Utrecht
Netherlands
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Participants (14)
2273 AB Voorburg
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
06410 Biot
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60323 Frankfurt Am Main
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17177 Stockholm
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00029 Helsinki
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22904 4195 Charlottesville
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81675 Muenchen
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1000 Bruxelles / Brussel
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00180 Helsinki
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09126 Cagliari
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
06903 Biot Sophia Antipolis
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17403 YORK
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10779 BERLIN
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1190 BRUXELLES FOREST
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Partners (6)
1253 Vandoeuvres
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6928 Manno
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4051 Basel
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1260 Nyon
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E1 4NS London
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NR4 7UZ Norwich
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