Objective
The CHIASMA’s Central Objective is to develop a new and improved Safety and Sustainable by Design Assessment framework based on innovative, in-project validated in vitro and in silico methods New Approach Methodologies (NAMs) and data for the next generation of hazard- & risk assessment of chemicals and materials. The developed NAMs cover main human target organs and exposure routes. The CHIASMA Assessment Framework will be based on an iterative multi-step approach based on Next Genaration Safety Assessment (NGSA) that combines chemocentric and biocentric approaches and NAMs and it will be able to predict regulatory relevant endpoints and long-term safety, together with absolute Life Cycle Impact Analysis (LCIA). Developed methods will be demonstrated for scienfic soundness and performances and for transferability (including to industrial environment), prior to submission to regulatory bodies.
Demonstration of the SSbD Framework in at least three chemicals/materials groups (PFAS, 2D materials for energy applications and (nano-)pesticides), supported by the assessment of socio-economic aspects and gap analyses in the context of existing methods.
Integration of the new & improved methods for expressing safety and health parameter into existing life-cycle and sustainability assessments methodologies and tools, as well as into the relevant applicable regulatory frameworks (incl. the SSbD framework).
Provision of accessible data for industry and public authorities, in order to ultimately support the wider implementation of the SSbD framework and its criteria.
The CHIASMA Project will run for 48 months. It is organised interdependent workflows, which will be broken down into 9 workpackages aligned with the scientific plan in order provide an optimum project-conduct and achievement of Project objectives.
Fields of science
Keywords
Programme(s)
Funding Scheme
HORIZON-RIA - HORIZON Research and Innovation ActionsCoordinator
4362 Esch Sur Alzette
Luxembourg
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Participants (14)
33100 Tampere
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1380 Cerknica
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
3721 MA Bilthoven
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6020 Innsbruck
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1040 Bruxelles / Brussel
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1433 As
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1070 Nicosia
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
157 80 ATHINA
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1210 Wien
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40225 Dusseldorf
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67063 Ludwigshafen Am Rhein
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00133 Roma
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1081 HV Amsterdam
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1040 BRUXELLES
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Partners (5)
133-791 SEOUL
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B15 2TT Birmingham
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SA2 8PP Swansea
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EH14 4AP Edinburgh
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
8600 Dubendorf
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