Multidimensional Integrated Quantitative Approach To Assess Safety And Sustainability Of Nanomaterials In Real Case Life Cycle Scenarios Using Nanospecific Impact Categories

Informations projet

INTEGRANO

N° de convention de subvention: 101138414

DOI

10.3030/101138414

Date de signature de la CE 23 Novembre 2023

Date de début 1 Janvier 2024

Date de fin 31 Decembre 2027

Financé au titre de

• Digital, Industry and Space

Coût total

€ 4 140 133,35

Contribution de l’UE

€ 3 985 648,75

Coordonné par

UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
Italy

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Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Websites, patent fillings, videos etc. (2)

IT platform for stakeholders engagement - SSbD Think tank
Project visual identity and website.

Documents, reports (2)

Final data management Plan
First data management Plan

Data management Plan

Publications

Peer reviewed articles (10)

Comparative toxicity and environmental impact assessments of sonochemically-synthesized CuO and Zn-doped CuO nanoparticles using zebrafish and LCA tools

Auteurs: Beatrice Negrini; Pamela Floris; Christian D’Abramo; Seyed Ahmad Aldaghi; Mattia Costamagna; Massimo Perucca; Melissa Saibene; Ilana Perelshtein; Anita Colombo; Patrizia Bonfanti; Paride Mantecca
Publié dans: Discover Nano, Numéro Volume 20, article number 51, 2025, ISSN 2731-9229
Éditeur: Discover Nano
DOI: 10.1186/S11671-025-04225-7

Current knowledge for implementing safe and sustainable by design across the life cycle of nanosilver textiles

Auteurs: Romero-Cantú, Héctor D.; Furxhi, Irini; Coelho, Carla Thais Pereira; Zanoni, Ilaria; Brigliadori, Andrea; Costa, Anna
Publié dans: Discover Sustainability, 2025, ISSN 2662-9984
Éditeur: Spring Nature
DOI: 10.1007/S43621-025-02092-X

A novel bio-based polyurethane foam for eco-friendly and sustainable refurbishment of heritage buildings

Auteurs: Fabrizio Ascione, Nicola Bianco, Rosa Francesca De Masi, Teresa Iovane, Giuseppe C. Lama, Margherita Mastellone, Gerardo Maria Mauro, Federica Recupido, Silvia Ruggiero, Alessandro Russo, Francesco Tariello, Giuseppe Peter Vanoli, Letizia Verdolotti
Publié dans: Energy Sources, Part A: Recovery, Utilization, and Environmental Effects, Numéro 48, 2025, ISSN 1556-7036
Éditeur: Informa UK Limited
DOI: 10.1080/15567036.2025.2605143

Comprehensive methodology for standardized ecotoxicological assessment of TiO2-based sunscreen leachates in aquatic environment

Auteurs: Roberta Nugnes, Giulia De Negri Atanasio, Elisabetta Perata, Erica Lertora, Lorenzo Dondero, Federica Robino, Francesca Tardanico, Cristina Capelli, Fabio Ghioni, Tania Cai, Dalia Gobbato, Norina Marciani, Roberta Miroglio, Matteo Zanotti Russo, Veronica Piazza, Marco Faimali, Chiara Gambardella, Francesca Garaventa, Elena Grasselli
Publié dans: Frontiers in Toxicology, Numéro 7, 2025, ISSN 2673-3080
Éditeur: Frontiers Media SA
DOI: 10.3389/FTOX.2025.1686954

Cutting-edge development of non-isocyanate polyurethane (NIPU) foams: from sustainable precursors to environmental impact evaluation

Auteurs: Federica Orabona, Federica Recupido, Giuseppe Cesare Lama, Krzysztof Polaczek, Francesco Taddeo, Tapio Salmi, Martino Di Serio, Letizia Verdolotti, Vincenzo Russo
Publié dans: Green Chemistry, Numéro 27, 2025, ISSN 1463-9262
Éditeur: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4GC05796A

Quantifying relevant exposure determinants and conditions of use for welding emissions

Auteurs: Antti Joonas Koivisto; Maxime Eliat; Michael Jayjock; Tareq Hussein; Alessia Nicosia
Publié dans: Open Research Europe, 2025, ISSN 2732-5121
Éditeur: European Commission
DOI: 10.12688/OPENRESEUROPE.19498.1

Functional silver-based nanomaterials affecting zebrafish development: the adverse outcomes in relation to the nanoparticle physical and chemical structure

Auteurs: Bonfanti P.; Colombo A.; Bengalli R.; Gualtieri M.; Zanoni I.; Blosi M.; Costa A.; Mantecca P.
Publié dans: Environmental Science: Nano, Numéro Numéro 6, 2024, 2024, ISSN 2051-8161
Éditeur: Royal Society of Chemistry (RSC)
DOI: 10.1039/D3EN00813D

Mechanism-enabled sustainability: Dynamic retro-Diels-Alder polyurethane network for reprocessable flexible foams

Auteurs: Krzysztof Polaczek, Federica Recupido, Federica Orabona, Loredana Tammaro, Giuseppe Cesare Lama, Zhanhua Wang, Giovanna Giuliana Buonocore, Letizia Verdolotti, Marino Lavorgna, Hesheng Xia
Publié dans: Chemical Engineering Journal, Numéro 537, 2026, ISSN 1385-8947
Éditeur: Elsevier BV
DOI: 10.1016/J.CEJ.2026.176175

Design of fully reprocessable composite non-isocyanate polyurethane (NIPU) foams from sustainable blends of cyclic carbonates

Auteurs: Federica Orabona; Federica Recupido; Krzysztof Polaczek; Giuseppe Cesare Lama; Martina Morra; Francesco Taddeo; Martino Di Serio; Tapio Salmi; Letizia Verdolotti; Vincenzo Russo
Publié dans: RSC Sustainability, Numéro Numéro 3, 2026, 2026, ISSN 2753-8125
Éditeur: RSC Sustainability
DOI: 10.1039/D5SU00946D

How credible is REACH regulation without transparency, quality criteria, assurance, and control?

Auteurs: Antti Joonas Koivisto; Michael Jayjock
Publié dans: Open Research Europe, 2025, ISSN 2732-5121
Éditeur: European Commission
DOI: 10.12688/OPENRESEUROPE.19510.1

Conference proceedings (23)

RES-22 Sister Projects Cluster Joint Poster for ANTHOS'26

Auteurs: SUNRISE, INTEGRANO, INSIGHT, ANALYST
Publié dans: 2026
DOI: 10.5281/ZENODO.19064485

Safe and Sustainable-by-Design Approach for Functional Bio-Silica Nanomaterials: LCA and LCC Comparisons

Auteurs: Filipa O. Gomes, Vinícius Cardos, Lorena Coelho, Natalia Dudchenko, Massimo Perucca, Benjamin Murray, Mattia Costamagna, Ahmad S. Aldaghi
Publié dans: 2025
Éditeur: ANM25

Playing with Chemistry to Build a Sustainable Future

Auteurs: Francesca Deganello, Maria Luisa Testa, Marco Russo, Chiara Aliotta, Chiara D’Errico, Andrea Ienco, Valentina Grasso.
Publié dans: 2025
Éditeur: CNR DSCTM

A new approach methodology for inhalation risk assessment of new nanoparticles

Auteurs: Giulia Motta, Maurizio Gualtieri, Melissa Saibene, Rossella Bengalli, Joan Cabellos, Franco Belosi, Maria Foti, Barbara Torsello, Paride Mantecca
Publié dans: 2024
Éditeur: Nanotox2024

An Integrated Approach to Evaluate the Safety of Innovative Materials for Water Treatment According to the SSbD Framework

Auteurs: Beatrice Negrini, Patrizia Bonfanti, Anita Colombo, Beatrice A. Brugger, Maurizio Gualtieri, Massimo Perucca, Paride Mantecca
Publié dans: 2026
Éditeur: SETAC26

A sustainable methodology for implementing a practical workflow to operationalise SSbD

Auteurs: Massimo Perucca, Benjamin Murray, Paride Mantecca
Publié dans: 2026
Éditeur: SETAC26

New methodologies for the hazard assessment of advanced nanomaterials: integration of mechanistic approaches in designed case studies

Auteurs: Rossella Daniela Bengalli, Maurizio Gualtieri, Stefano Cervellera, Giulia Motta, Francesca Deganello, Ilaria Zanoni, Anna Costa, Massimo Perucca, Paride Mantecca
Publié dans: 2025
Éditeur: EUROTOX25

A NEW APPROACH METHODOLOGY TO EVALUATE THE BIOLOGICAL IMPACT OF SILVER NANOMATERIALS IN HUMAN LUNG

Auteurs: Giulia Motta, Rossella Bengalli, Maurizio Gualtieri, Paride Mantecca
Publié dans: 2024
Éditeur: 69° Conference GEI-SIBSC

IN VITRO NEW APPROACH METHODOLOGIES (NAMS) FOR THE HAZARD ASSESSMENT OF NANOMATERIALS

Auteurs: R. Bengalli, G. Motta, P. Bonfanti, A. Colombo, M. Gualtieri, P. Mantecca.
Publié dans: 2025
Éditeur: Conference GEI-SIBSC

Hazard assessment of advanced nanomaterials: the INTEGRANO testing strategy to support the Safe and sustainable by design framework

Auteurs: Rossella Daniela Bengalli, Sara Marchetti, Stefano Cervellera, Beatrice Negrini, Alessandra Lama, Patrizia Bonfanti, Anita Colombo, Massimo Perucca, Maurizio Gualtieri,Paride Mantecca
Publié dans: 2026
Éditeur: ANTHOS26

Reference and new approach methodologies in the evaluation of new (nano) materials in the safe and sustainable by design framework: the INTEGRANO project experience.

Auteurs: M. Gualtieri, R.D. Bengalli, S. Cervellera, S. Marchetti, F. Deganello, P. Mantecca
Publié dans: 2025
Éditeur: Future Material 2025

Synthesis and Characterization of Reprocessable Composite Flexible Polyurethane Foams with Self-Reorganizing Diels-Alder (DA)-Based Covalent Adaptable Networks (CANs)

Auteurs: Federica Recupido, Krzysztof Polaczek, Federica Orabona, Giuseppe Cesare Lama, Marino Lavorgna, Loredana Tammaro, Qifan Zhao, Xili Lu, Hesheng Xia, Letizia Verdolotti
Publié dans: 2025
Éditeur: International Conference on Renewable Resources & Biorefineries (RRB)

Multidimensional Integrated Quantitative Approach To Assess Safety And Sustainability Of Nanomaterials In Real Case Life Cycle Scenarios Using Nanospecific Impact Categories

Auteurs: Stefano Cervellera
Publié dans: 2025
Éditeur: Università degli Studi di Milano Bicocca

Refinement of Fish Embryo Toxicity Test To Assess Ecotoxicological Effects of Nanoparticles

Auteurs: Alessandra Lama, Pamela Floris, Patrizia Bonfanti, Anita Colombo, Maurizio Gualtieri, Paride Mantecca
Éditeur: SETAC26

Accelerating Safe and Sustainable by Design adoption: the role of INTEGRANO, IRISS, and PARC projects.

Auteurs: Chiara Stopponi, Stefania Truffa, Doris Völker, Emma Strömberg
Éditeur: ANTHOS26

INTEGRANO quantitative-based methodology to SSbD enabling R&I implementors’ acceptance

Auteurs: Massimo Perucca, Benjamin Murray, Andrea Garrone, Rossella Daniela Bengalli, Maurizio Gualtieri, Paride Mantecca, Lorena Coelho, Andreia Monteiro
Publié dans: 2026
Éditeur: ANTHO26

EMBRYOTOXIC EFFECTS OF ZnO NANOPARTICLES IN ZEBRAFISH: INFLUENCE OF THE TESTING CONDITIONS

Auteurs: Alessandra Lama, Pamela Floris, Paride Mantecca, Anita Colombo, Patrizia Bonfanti
Publié dans: 2025
Éditeur: Conference GEI-SIBSC

A LUNG CO-CULTURE MODEL TO EXPLORE THE INFLAMMATORY EFFECTS DETERMINED BY COMBINED EXPOSURE TO to PM2.5, SARS-CoV-2 AND NANO-ANTIVIRAL AGENTS

Auteurs: S. Marchetti, M. Gualtieri, R. Bengalli, A. Colombo, P. Mantecca
Publié dans: 2025
Éditeur: Conference GEI-SIBSC

Reference and new approach methodologies in the evaluation of new (nano) materials in the safe and sustainable by design framework: the INTEGRANO project experience.

Auteurs: M. Gualtieri, R.D. Bengalli, S. Cervellera, S. Marchetti, F. Deganello, P. Mantecca
Publié dans: 2025
Éditeur: Future Material 2025

Ecotoxicological Assessment of Silver Nanoparticles in the Marine Environment: A Multispecies Approach

Auteurs: R. Nugnes, C. Gambardella, R. Miroglio, L. Lazzeri, F. Maccaroni, E. Costa, V. Piazza, L. Zanetti, M. Faimali, A.L. Costa, M. Blosi, I. Zanoni, M. Gualtieri, P. Mantecca, F. Garaventa
Publié dans: 2025
Éditeur: SETAC Italian Language Branch

Integrating SSbD Principles in the Synthesis of Bio-SiO2 Functionalized with TiO2 for Sustainable Solutions

Auteurs: Filipa O. Gomes, Vinícius Cardos, Lorena Coelho, Natalia Dudchenko, Massimo Perucca, Benjamin Murray
Publié dans: 2025
Éditeur: EUROMAT25

Addressing stakeholders’ negotiation process in SSbD decision making for INTEGRANO project nano-enabled solutions

Auteurs: M. Perucca, B. Murray, A. Garrone, F. O. Gomes, V. Cardoso, L. Coelho, A. Monteiro, I. Zanoni, S. Ortelli, C. Artusi, M. Serantoni, M. Blosi, A. Costa, F.Deganello, L.Boggioni, L. Verdolotti, F. Recupido, G. Lama, I. Tonani Tomasoni, V. Battistello, M. Ge
Publié dans: 2025
Éditeur: 22nd International Conference on Nanosciences & Nanotechnologies (NN25)

Synthesis of fully bio-based and re-processable self-blowing composite Non Isocyanate Polyurethane Foams

Auteurs: Federica Orabona, Krzysztof Polaczek, Federica Recupido, Giuseppe Cesare Lama,Francesco Taddeo, Tapio Salmi, Martino Di Serio, Vincenzo Russo, R. Marzella, Letizia Verdolotti
Publié dans: 2025
Éditeur: International Conference on Renewable Resources & Biorefineries (RRB)

Other (2)

"Extended Data for ""Particle emission rates and conditions of use for the cutting of biobased composite polyurethane foam"""

Auteurs: Koivisto, Antti Joonas
Publié dans: 2025
DOI: 10.5281/ZENODO.15727267

13th Venice Training School 2025 - teaching materials

Auteurs: Alfaro Serrano, Beatriz; Hristozov, Danail; Resch, Susanne; GARCIA, AMAIA; Luhmann, Hilfegard; Friesl, Judith; Hofstätter, Norbert; Hofer, Sabine; Himly, Martin
DOI: 10.5281/ZENODO.17305647