Project description
Decoding the multi-isotopic composition of sulphur-bearing materials
Many bacteria play a role in the sulphur cycle via so-called dissimilatory sulphur metabolisms including sulphate reduction, reduced sulphur oxidation, and sulphur disproportionation. Sulphur and oxygen isotope discrimination during this metabolic activity is modulated by diagenesis (physical and (bio)chemical processes that alter sediments) before being preserved in sedimentary rocks. The multi-isotope composition of these rocks encodes valuable information about microbial activity, environmental conditions and elemental cycles. The ERC-funded ISoSCOPE project aims to improve interpretation of this encoded information with better understanding of metabolic isotope fractionation and the impacts of diagenesis on its preservation. Metabolic-isotopic models will be embedded in ecosystem models, and the results will be compared to microfluidic experiments and environmental data.
Objective
Dissimilatory S metabolisms impart large S and O isotope fractionations, which are modulated by a suite of (bio)chemical reactions and physical processes (i.e. diagenesis) and ultimately preserved in the reduced and oxidized products of sedimentary S cycling (e.g. pyrite, carbonate-associated sulfate). The multi-isotope composition of such compounds encodes valuable information about microbial activity, environmental conditions, and elemental cycles. Robust interpretation of these signals requires mechanistic understanding of both the metabolic isotope fractionation itself and the impacts of diagenesis on its ultimate preservation. Such understanding is currently limited by simplified models of isotopic fractionation in dissimilatory S metabolisms, and by difficulty in capturing spatio-temporally heterogeneous diagenesis in reaction-transport models. We pioneered metabolic-isotopic models (MIMs), which account for the thermodynamics and kinetics of enzymatic reactions and turn empirical multi-isotope correlations into causal relationships. Here, I propose to develop and apply novel, experimentally-validated MIMs of the three most ecologically important S metabolisms—sulfate reduction, reduced S oxidation, and S disproportionation. By embedding these MIMs in a hierarchy of ecosystem models of increasing dimensionality and sophistication, and comparing the results to microfluidic experiments and environmental data, we will gain quantitative, nuanced insight into: (i) the controls on multi-isotope fractionation in metabolic S cycling, (ii) its heterogeneous manifestation in aqueous and solid compounds, and (iii) the use of these compounds' isotopic compositions to robustly probe S cycling on microscopic to global scales, microenvironmental conditions, and depositional parameters, in both modern and ancient settings. With S as a test case, we blaze a path to similar treatment of the processes that govern the isotopic composition of many other natural materials.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- natural scienceschemical scienceselectrochemistryelectrolysis
- natural sciencesbiological sciencesecologyecosystems
- medical and health sciencesbasic medicinephysiology
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Programme(s)
- HORIZON.1.1 - European Research Council (ERC) Main Programme
Topic(s)
Funding Scheme
HORIZON-ERC - HORIZON ERC GrantsHost institution
7610001 Rehovot
Israel