Description du projet
Les oscillations thêta et bêta dans l’exécution de l’action
Les «oscillations» synchronisées à grande échelle de l’activité neuronale entre diverses zones du cerveau sont associées au traitement d’informations complexes requérant plusieurs régions cérébrales. Ce processus englobe la prédiction sensorimotrice, l’intégration sensorielle, la planification, l’exécution et l’évaluation du mouvement. Avec le soutien du programme Actions Marie Skłodowska-Curie, le projet THE-BET se propose d’étudier les relations entre l’activité thêta (environ 4-8 Hertz) et bêta sensorimotrice (environ 13-30 Hertz) de la ligne médiane frontale et leurs contributions à l’exécution et au contrôle de l’action lors de l’exécution d’actions orientées vers un but. L’étude s’appuiera sur de récentes données à haute densité enregistrées par magnétoencéphalographie chez des participants à de nombreux essais de tâches génératrices de conflits. Les données permettront d’élaborer de nouveaux modèles neurocomportementaux du traitement des conflits et des erreurs.
Objectif
Human actions are complex processes that require the coordination of numerous brain areas responsible for sensorimotor prediction, sensory integration, action planning, decision-making, movement execution, and performance evaluation. Various neural oscillations in different frequency bands, including delta, theta, alpha/mu, beta, and gamma, have been identified as markers of these processes. However, their precise functional significance, interrelationships, and specificity remain poorly understood. This proposal is dedicated to investigating the neural mechanisms involved in action execution and monitoring, with a specific focus on the roles of frontal midline theta and sensorimotor beta activity. The primary objective is to unravel the relationships between these neural activities and their contributions to the performance of goal-oriented actions. To achieve this, I will record a new high-density MEG dataset with participants performing a large number of trials involving conflict-inducing tasks. The proposal is centered around three 3 sub-projects (SPs). Sub-Project 1 (SP1) focuses on unraveling the functional specificity of frontal theta(s) in goal-related actions. The main hypothesis of SP1 is that conflict-related, error-related, and monitoring-related theta activity exhibits different temporal dynamics (e.g. burst vs. sustained oscillation) and originates from distinct neural sources. Sub-Project 2 (SP2) will investigate the functional connectivity between theta(s) and beta activity during action execution. Beta activity in individual trials occurs in brief, sporadic bursts, rather than in sustained oscillations. SP2 will explore long-range directed connectivity measures between action-monitoring areas and M1 during motor execution, considering the burst-like nature of beta and theta. Sub-Project 3 (SP3) will combine results from SP1 and SP2 and focus on neuro-behavioural joint modeling of conflict and error processing using Drift Diffusion Models.
Mots‑clés
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Appel à propositions
(s’ouvre dans une nouvelle fenêtre) HORIZON-MSCA-2023-PF-01
Voir d’autres projets de cet appelRégime de financement
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European FellowshipsCoordinateur
75794 Paris
France