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Formose Reactions on Microdroplets (FROM)

Project description

Geysers and microdroplets: unveiling life’s origins

The origins of life remain one of science’s greatest mysteries, with the role of specific environmental factors still under exploration. While water microdroplets have recently been recognised as a unique reaction medium, their potential in prebiotic chemistry is largely unexplored. Additionally, the mechanisms through which complex organic molecules such as carbohydrates form from simpler compounds remain unclear. Supported by the Marie Skłodowska-Curie Actions programme, the FROM project hypothesises that geysers could have acted as catalysts for the synthesis of these molecules. Specifically, it explores the role of water microdroplets in CO2 reduction and the subsequent formation of carbohydrates through the formose reaction. This research offers a high-risk, high-reward approach to understanding the molecular origins of life.

Objective

I propose to examine the importance of water microdroplets sprayed from geysers as a reaction medium in prebiotic chemistry, with the goal of providing evidence for CO2-reduction to formaldehyde and following synthesis of carbohydrates from formaldehyde via the formose reaction. Water microdroplets have recently been proven to be a unique reaction medium, but the importance of microdroplets for the origins of life remains largely unexplored. This fellowship application proposes geysers as a catalyst for synthesis of complex organic molecules at the origin of life – a new hypothesis which has previously not been explored. This is a high risk, high gain proposal and the new scientific skills obtained during the fellowship will be highly valuable for a research career at the interface of organic synthesis and microdroplet chemistry. The project will be carried out over two years with Prof. Michael Pittelkow at the University of Copenhagen where all synthetic chemistry, kinetic experiments and characterization of products will be performed.

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

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(opens in new window) HORIZON-MSCA-2023-PF-01

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Coordinator

KOBENHAVNS UNIVERSITET
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 230 774,40
Address
NORREGADE 10
1165 KOBENHAVN
Denmark

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Region
Danmark Hovedstaden Byen København
Activity type
Higher or Secondary Education Establishments
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Total cost

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