Project description
A non-human primate model for surgical training
Over 50 years ago, ethical principles were designed to improve the welfare of animals used in research, focusing on the replacement of animals with alternative techniques and models. The ERC-funded PRISM project aims to replace the use of non-human primates (NHP) in invasive neurosurgical procedures for training purposes. The team aims to develop an NHP model that closely mimics the anatomical and physiological characteristics of real NHPs and can be used by surgeons to practice complex procedures in a controlled, ethical, and risk-free environment. This approach will help improve surgical education, overcoming the need for live animals.
Objective
The PRISM project addresses critical challenges in neurosurgical training involving non-human primates (NHPs) within the framework of the 3Rs (Replacement, Reduction, Refinement) endorsed by the EU. NHPs are indispensable models in biomedical research, particularly in neurosciences, due to their close phylogenetic relationship with humans. However, invasive procedures on NHPs, including cranial surgeries and targeted ablations, pose ethical dilemmas and require highly skilled personnel. This project introduces a groundbreaking solution by developing the first hyper-realistic model for hands-on surgical training in NHPs. Collaborating with UpSurgeOn, experts in 3D simulation for human neurosurgery, PRISM aims to create a safe and ethical training environment for young researchers working with NHP. The project's objectives include the design of a hyper-realistic NHP model, the organization of pilot courses, and devising strategies for commercialization. PRISM promises enhanced visualization, tactile learning experiences, customizability, and ethical training, ultimately fostering career development, animal welfare, and research quality. Successful implementation will set a new standard in NHP neurosurgical education with global potential.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- natural sciencesbiological scienceszoologymammalogyprimatology
- natural sciencesbiological sciencesneurobiology
- medical and health sciencesclinical medicinesurgery
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Keywords
Programme(s)
- HORIZON.1.1 - European Research Council (ERC) Main Programme
Funding Scheme
HORIZON-ERC-POC - HORIZON ERC Proof of Concept GrantsHost institution
5037 AB Tilburg
Netherlands