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WOMED: an innovative intrauterine biodegradable polymer-based drug-delivery platform

Project description

Innovations in uterine disorder treatments for women

Women worldwide face significant challenges with uterine disorders such as excessive bleeding and fertility issues, including fibroids and endometriosis, which are critical unmet needs in women’s health. The withdrawal of Esmya, a widely used fibroid treatment, has left a gap in effective options for patients. Moreover, women suffering from endometriosis often endure poorly managed pain, highlighting the pressing need for improved treatments. Addressing these issues, the EIC-funded WOMED project introduces Womed Leaf, a drug-free intrauterine device designed to prevent adhesions and restore fertility. Building on Leaf’s innovative design, the project aims to develop a uterine drug delivery platform featuring Fibroid, a preoperative treatment for fibroids, and ReLeaf, a non-hormonal solution for managing endometriosis-related pain.

Objective

Every woman experiences some form of uterine disorder during her lifetime, including excessive bleeding, pelvic pain, and fertility issues, posing an enormous burden for women worldwide. Current treatments have limitations & painful side effects. Fibroids and endometriosis are two of the most relevant unmet needs in women health. For fibroids, an extremely common condition affecting 51% of women between 35-49, the withdrawal of Esmya, a highly appreciated treatment, has left a gap in effective options. Meanwhile, women with endometriosis (10% women in reproductive years) suffer incapacitating pain that is poorly managed with systemic analgesics. There is an urgent need for better treatments.

Womed was founded in Montpellier by Gonzague Issenmann, a serial MedTech entrepreneur, to revolutionize the women health industry by changing the paradigm of uterine disorders treatment. Womed develops safe and effective local intrauterine therapies. Our unique and patented copolymer structure allows for easy insertion, biodegradability and sustained and controlled local drug delivery. Our first product, Womed Leaf, is a drug-free intrauterine device that prevents adhesions and restores fertility. Based on Leaf’s design, we are developing a uterine drug delivery platform with Fibroid, a preoperative treatment for fibroids, and ReLeaf, a nonhormonal treatment to alleviate endometriosis-related pain.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance

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Call for proposal

(opens in new window) HORIZON-EIC-2023-ACCELERATOR-01

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Coordinator

WOMED
Net EU contribution
€ 2 493 809,50
Address
1919 ROUTE DE MENDE BATIMENT BALARD - CIT
34090 MONTPELLIER
France
SME
Yes
Region
Occitanie Languedoc-Roussillon Hérault
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost
€ 3 562 697,00