Descrizione del progetto
Individuare le carie grazie a un’innovativa tecnologia di scansione intraorale
La malattia della carie, che colpisce 2 miliardi di adulti e 500 milioni di bambini a livello globale, comporta un notevole onere sanitario ed economico. Gli attuali metodi diagnostici per individuarla, basati sull’esame visivo e sulla radiografia dentale, possono mancare il rilevamento di lesioni poco visibili e determinano rischi di esposizione alle radiazioni, lacune che impediscono un monitoraggio tempestivo e accurato della progressione delle carie. In questo contesto, il progetto IOSC, finanziato dall’UE, utilizzerà la scansione intraorale basata sulla fluorescenza e sulla tecnologia a infrarossi per garantire un monitoraggio preciso. Guidato dall’Università di Malta, il progetto condurrà studi clinici per valutare l’accuratezza di questa tecnologia rispetto ai metodi convenzionali, fornendo risultati che promettono un monitoraggio più sicuro e non invasivo. Che sia di conferma o di perfezionamento dei metodi attualmente a disposizione, questa ricerca darà forma alle future cure dentistiche in ambito di carie.
Obiettivo
Caries disease is a global health and economy burden experienced by 2 billion of adults and 500 millions of children around the world. Visual exam and dental radiography are the standard methods for diagnosing and monitoring dental caries and present shortcomings: subtle lesions of caries cannot be visual or radiographically detected and are highly sensitive to the examiner; besides it, X-rays involve ionizing radiation which limits monitoring at small intervals and has structures superimposition. Recently, TRIOS 4 (3Shape, Copenhagen, Denmark) intraoral scanning (IOS) brings caries aid monitoring tool based on fluorescence and infrared technologies. Despite in vitro studies suggesting its applicability, there is no clinical evidence of its accuracy (true positives and negatives). In this context, the goal of this project is to clinically assess the accuracy of this novel approach for detecting and monitoring dental caries. After ethics approval, I will examine patient’s teeth under dental caries treatment in Faculty of Dental Surgery of University of Malta using visual exam and dental radiography, then I will scan teeth with TRIOS 4 IOS using fluorescence and infrared technologies. Using these clinical digital data, I will output: 1) the accuracy of TRIOS4 compared with standard methods; 2) if the result changes between professionals - in a multicentre approach. If firmly established, it will be a way to change caries monitoring in a safe and non-invasive approach; if not, it will provide scientific evidence for improvement, future studies and development of new tools. The results will be interesting for scientist, dentists, industry and citizens, as caries is a common disease with high global prevalence. For reaching such audience, communication, dissemination and exploitation is planned using open access practices through data repository, green and gold routes, as well as in mass media.
Campo scientifico
Programma(i)
Argomento(i)
Meccanismo di finanziamento
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European FellowshipsCoordinatore
2080 MSIDA
Malta