Comparative signature of Marburg virus cell activation as a blueprint for the identification of antiviral targets against newly emerging viruses

Project Information

COMBINE

Grant agreement ID: 101191739

DOI

10.3030/101191739

EC signature date 7 November 2024

Start date 1 January 2025

End date 31 December 2029

Funded under

• Health

Total cost

€ 7 285 043,75

EU contribution

€ 7 285 043,75

Coordinated by

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

iDeepLC: Chemical Structure Information Yields Improved Retention Time Prediction of Peptides with Unseen Modifications

Author(s): Alireza Nameni, Arthur Declercq, Ralf Gabriels, Robbe Devreese, Sven Degroeve, Amélie De Maesschalck, Maarten Dhaenens, Cristina Chiva, Eduard Sabidó, Lennart Martens, Robbin Bouwmeester
Published in: Analytical Chemistry, Issue 98, 2026, ISSN 0003-2700
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACS.ANALCHEM.5C08017

The <i>Escherichia coli</i> PeptideAtlas Build: Characterizing the Observed <i>Escherichia coli</i> Pan-Proteome and Its Post-Translational Modifications

Author(s): Caroline Jachmann, Zhi Sun, Kevin Velghe, Florence Arsène-Ploetze, Aurélie Hirschler, Jasper Zuallaert, Christine Carapito, Robbin Bouwmeester, Kay Nieselt, Eric W. Deutsch, Lennart Martens, Ralf Gabriels, Tim Van Den Bossche
Published in: Journal of Proteome Research, Issue 25, 2026, ISSN 1535-3893
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACS.JPROTEOME.5C00902

msqrob2TMT: Robust Linear Mixed Models for Inferring Differential Abundant Proteins in Labeled Experiments With Arbitrarily Complex Design

Author(s): Stijn Vandenbulcke, Christophe Vanderaa, Oliver Crook, Lennart Martens, Lieven Clement
Published in: Molecular &amp; Cellular Proteomics, Issue 24, 2025, ISSN 1535-9476
Publisher: Elsevier BV
DOI: 10.1016/J.MCPRO.2025.101002

Transfer learning in DeepLC improves LC retention time prediction across substantially different modifications and setups

Author(s): Robbin Bouwmeester, Alireza Nameni, Arthur Declercq, Robbe Devreese, Kevin Velghe, Vladimir Gorshkov, Pelayo A. Penanes, Frank Kjeldsen, Magali Rompais, Christine Carapito, Ralf Gabriels, Lennart Martens
Published in: Nature Communications, Issue 17, 2026, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-026-68981-5

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

Author(s): Jan Schlegel, Christian Sieben
Published in: FEBS Letters, 2026, ISSN 0014-5793
Publisher: Wiley
DOI: 10.1002/1873-3468.70347

MultiStageSearch: An Iterative Workflow for Unbiased Taxonomic Analysis of Pathogens Using Proteogenomics

Author(s): Julian Pipart, Tanja Holstein, Lennart Martens, Thilo Muth
Published in: Journal of Proteome Research, Issue 24, 2025, ISSN 1535-3893
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACS.JPROTEOME.4C00901

TIMS ² Rescore: A Data Dependent Acquisition-Parallel Accumulation and Serial Fragmentation-Optimized Data-Driven Rescoring Pipeline Based on MS ² Rescore

Author(s): Arthur Declercq, Robbe Devreese, Jonas Scheid, Caroline Jachmann, Tim Van Den Bossche, Annica Preikschat, David Gomez-Zepeda, Jeewan Babu Rijal, Aurélie Hirschler, Jonathan R Krieger, Tharan Srikumar, George Rosenberger, Claudia Martelli, Dennis Trede, Christine Carapito, Stefan Tenzer, Juliane S Walz, Sven Degroeve, Robbin Bouwmeester, Lennart Martens, Ralf Gabriels
Published in: Journal of Proteome Research, Issue 24, 2025, ISSN 1535-3893
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACS.JPROTEOME.4C00609

Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface

Author(s): Lukas Broich, Hannah Wullenkord, Maria Kaukab Osman, Yang Fu, Mathias Müsken, Peter Reuther, Mark Brönstrup, Christian Sieben
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-58935-8

MLMarker: a machine learning framework for tissue inference and biomarker discovery

Author(s): Tine Claeys, Sam van Puyenbroeck, Kris Gevaert, Lennart Martens
Published in: Genome Biology, Issue 27, 2026, ISSN 1474-760X
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S13059-026-04125-8

omicsGMF: a multi-tool for dimensionality reduction, batch correction and imputation in bulk- and single-cell proteomics

Author(s): Alexandre Segers, Cristian Castiglione, Christophe Vanderaa, Lennart Martens, Davide Risso, Lieven Clement
Published in: Nature Communications, Issue 17, 2026, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-026-73402-8

Collisional Cross-Section Prediction for Multiconformational Peptide Ions with IM2Deep

Author(s): Robbe Devreese, Alireza Nameni, Arthur Declercq, Emmy Terryn, Ralf Gabriels, Francis Impens, Kris Gevaert, Lennart Martens, Robbin Bouwmeester
Published in: Analytical Chemistry, Issue 97, 2025, ISSN 0003-2700
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACS.ANALCHEM.5C01142