Objective
Iron deficiency is a known public health concern, particularly for vulnerable groups (children and pregnant women), affecting around 1.62 billion people worldwide. In plant-based diets, the sources of iron are non-heme, less bioaccessible compared to the iron (heme iron) found in animal products. Despite its prevalence, effective dietary interventions focused on micronutrients deficiencies remain limited, mostly due to a lack of understanding of the fate of iron carriers during digestion of complex foods. The objective of FooDIS is to fill this research gap, focus on the fate of bioavailable iron during in vitro digestion and adsorption, to assist in the design of sustainable and innovative iron-rich foods. FooDIS will explore the potential of phytoferritins, plant iron-binding proteins, as effective carriers of bioavailable non-heme iron in plant-based foods. The hypothesis is that phytoferritins can be used as iron carriers, by creating specific interactions with other food components. By testing this hypothesis, we will learn how to enhance the bioavailability of non-heme iron in plant-based foods. The objectives of FooDIS will be achieved through a multidisciplinary approach, integrating the study of phytoferritins digestion in food using INFOGEST-standardized protocol, advanced spectroscopy (synchrotron) and ICP-MS analyses, and in vitro absorption models containing mucus-producing cells (Caco2/HT29MTX). The study, starting with simple and moving to complex model systems, will bring detailed insights of the fate of iron during digestion and its absorption, but also analyze iron speciation and interaction with other food components, leading to new, important discoveries on the mechanism of gut iron absorption. The outcomes will have societal and scientific impact, providing knowledge for the design of novel plant-based iron delivery systems, not only contributing to address the nutritional needs of more sustainable diets but to improve global health outcomes.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences health sciences nutrition
- natural sciences physical sciences optics spectroscopy
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
8000 Aarhus C
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.