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Uncovering Educational and Health Inequalities through Socioeconomic–Genotype Interactions (IneqGen)

Project description

Understanding how genetics and family shape inequality

Children’s educational achievement and health are strongly influenced by their family environment, yet the ways in which socioeconomic circumstances interact with genetic predispositions remain poorly understood. Supported by the Marie Skłodowska-Curie Actions programme, the IneqGen project is investigating how family socioeconomic resources shape the influence of children’s genetic propensities on education and health. Using causal methods and family-based genetic designs, it will examine the impact of parenting practices, expectations, and health behaviours. The combination of genetics and social science is expected to offer new insights into the mechanisms driving intergenerational inequality. Ultimately, the project’s goal is to inform evidence-based strategies to promote equal opportunities.

Objective

Children from socioeconomically advantaged families tend to achieve higher levels of education and enjoy better health. Research shows that this phenomenon is at least partially explained by differences in parenting practices shaped by parental resources, for example, in how parents support learning, guide school decisions, or promote healthy behaviours. However, this previous research focuses on observable traits, overlooking that the child’s genotype - an early, often hidden factor - can be amplified, triggered, or compensated for by the family socioeconomic environment and shapes later educational and health outcomes.

The recent unprecedented availability of large-scale molecular genetic data now makes it possible to integrate genetic information with rich survey and administrative datasets. This enables IneqGen to study whether, and how, parents with different socioeconomic resources compensate for, amplify, or trigger their children’s genetic propensities, thereby sustaining or reinforcing social inequalities. IneqGen seeks to understand how (dis)advantaged parents pass on their (dis)advantages by examining whether the influence of children’s genetic propensities varies by family socioeconomic status. IneqGen is at the forefront of the emerging field of using molecular genetics data to understand social inequalities by applying causal designs and using family genetic data.

This project makes three main contributions. First, the project will deliver theoretical innovation by developing the first comprehensive, interdisciplinary typology of how family socioeconomic background moderates genetic influences on education and health. Second, it will achieve causal identification by combining exogenous variation from the Norwegian oil boom with trio-based genetic designs. Third, it will uncover mechanisms, such as parental expectations, involvement, and health-related practices, through which family socioeconomic background moderates genetic propensities.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Net EU contribution
€ 260 347,92
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom
Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data