Objective
Development of a Nanohybrid System Based Wearable Microfluidic Photoelectrochemical Sensor for the On-Demand cTnI Detection
The Acute Myocardial Infarction (AMI) demands instant diagnosis, since the currently existing technologies remain invasive, expensive, time-consuming, and confined to clinical setups. The project NANOPEC proposed for the MSCA PF application hosts an innovative solution with the development of a wearable, biorecognition-free, microfluidic photoelectrochemical (PEC) saliva sensor for the ultrasensitive detection of cardiac troponin (cTnI). Fundamentally, it lies in a unique zinc oxide tetrapod-graphene quantum dot (ZnOTPD/GQD)-based nanohybrid system, while GQD will be derived sustainably from plastic waste. Embedding this into a flexible, wearable patch will enable the on-demand real-time monitoring of cTnI levels. This project relies on the following key deliverables: Development of GQD with quantum yield > 50% with photoinduced charge transfer efficiency over 85% within the nanohybrid, Fabrication of a durable, microfluidic PEC patch withstanding at least 50 cycles while keeping a stable performance, ultrasensitive detection with an expected limit of detection < 5 pg/ml, and validation of the sensor performance with artificial saliva matrices with reproducibility (expected RSD under 8%) and robustness against common interfering analytes. By interlinking nanotechnology, material science, and wearable diagnostics, NANOPEC will open up a way for a low-cost, scalable, sustainable, non-invasive, on-set diagnostic tool, which will improve clinical outcomes and reduce the global mortality rate.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2025-PF
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
LT-44029 Kaunas
Lithuania
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.