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NbMEA: Niobium Multi-Electrode Arrays for Next-Generation ofElectromyographic Interfaces

Ziel

Intramuscular electromyography (iEMG) is the clinical gold standard for diagnosing neuromuscular disorders, yet the dominant material used by doctors is stainless-steel, and has remained unchanged for decades. These electrodes provide only a single or few recording channel per wire, suffer from corrosion and nickel sensitization risks, require separate polymer insulation that doubles the wire diameter and introduces delamination failure modes, and are MRI-incompatible. During the ERC-funded GRASPAGAIN project (StG 101118089), we discovered that niobium fine wire electrodes offer a transformative alternative. Niobium provides an answer to these problems — all in one MRI-safe, non-allergenic material that eliminates the need for separate polymer insulation. Preliminary human recordings confirmed that niobium electrodes yield more discriminable motor units per insertion than co-implanted stainless-steel, consistent with higher spatial selectivity from a smaller recording area. This project will develop and validate a new class of niobium electrodes (NbMEA), enabling multi-channel recordings from a single implant, lowering risk and pain for patients. The fabrication exploits niobium’s unique properties, simplifying manufacturing and supply chain relative to polymer-insulated electrodes. We will optimize the microfabrication pipeline, validate multi-channel motor unit decomposition in human volunteers, file a patent, and prepare the business plan for a spin-out targeting the USD 1–2 billion global EMG market. The NbMEA will establish a new device class for clinical neurophysiology, motor control research, and chronic neural interfaces, enabling multi-channel iEMG recording across muscle anatomies at unprecedented scale from a single needle insertion

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Programm/Programme

Thema/Themen

Finanzierungsplan

HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants

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Aufforderung zur Vorschlagseinreichung

(öffnet in neuem Fenster) ERC-2026-POC

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Gastgebende Einrichtung

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Netto-EU-Beitrag
€ 150 000,00
Adresse
FREYESLEBENSTRAßE 1
91058 Erlangen
Deutschland
Region
Bayern Mittelfranken Erlangen, Kreisfreie Stadt
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
Keine Daten

Begünstigte (1)