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Nanotechnologies for Bio-inspired polySaccharides: biological decoys designed as knowledge-based, multifunctional biomaterials

Objective

The NanoBioSaccharides project convenes an interdisciplinary consortium of scientists from academia and industry to develop and exploit nanotechnologies for the generation of knowledge-based, multifunctional, bio-inspired polysaccharides to be used as in telligent, sustainable, environment-friendly and consumer-safe biomaterials. As an example, chitosans generated from shrimp shell and squid pen wastes are an extremely versatile class of biopolymers with superior structural properties and supreme biologi cal activities. However, todays chitosans are ill-defined mixtures of poorly soluble, inhomogeneous polymers, explaining the lack of reproducibility in bio-medical and pharmaceutical applications that have so far prevented their successful commercial use. Other examples of versatile bioactive polysaccharides yet inappropriately exploited include plant pectins and alginates, and human and animal glycosaminoglycans. The core partners of the NanoBioSaccharides project have recently developed a novel concept for the relationship between the physico-chemical properties of chitosans and their biological activities. Based on this 'decoy' concept, we will now use nano- and bio-technologies for the production, modification, and characterisation of third generatio n bio-inspired polysaccharides. We will develop tailor-made chitosan nanoparticles for drug and gene delivery, and bio-inspired chitosan hydrogels for cell and tissue enigneering. By developing nanotechnologies suitable for polysaccharides, the third and so far neglected and unexploited class of information-bearing biopolymers, the NanoBioSaccharides project will secure the EU a head start in this emerging and promising field of functional bio-inspired materials. The project will integrate the whole pro duct chain from the raw materials to the novel, nano-structured biomaterials to be used in biotechnological applications in medicine, pharmacology, cosmetics, agriculture, and food sciences.'

Call for proposal

FP6-2003-NMP-TI-3-MAIN
See other projects for this call

Coordinator

WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER
Address
Schlossplatz 2
Muenster
Germany

Participants (14)

EZUS LYON 1
France
Address
43 Bd Du 11 Novembre 1918 - Bt. L'atrium
Villeurbanne
CARE SENSE CONSULTING
Germany
Address
Merschwiese 2A
Senden
DANISCO A/S
Denmark
Address
Langebrogade 1
Copenhagen K
GILLET CHITOSAN EURL
France
Address
Centre D'affaires Le Cahn - 17 Rue Laurent Bonnevay
Nancy
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
Spain
Address
Pazo De San Xerome - Praza Do Obradoiro, S/n
Santiago De Compostela
ADVANCED IN VITRO CELL TECHNOLOGIES S.L.
Spain
Address
Baldiri Reixac 10-12
Barcelona
UNIVERSITAETSKLINIK MUENSTER
Germany
Address
Domagkstrasse 5
Muenster
CUTECH SRL
Italy
Address
Corso Stati Uniti 23/I
Padova
UNIVERSITY OF HYDERABAD
India
Address
Central University P.o., Gachibowli
Hyderabad
MAHIDOL UNIVERSITY
Thailand
Address
Rama Vi Road, Ratchathewi
Bangkok
PRINCE OF SONGKLA UNIVERSITY
Thailand
Address
15 Karnjanawanitch, Hat-yai
Songkla
LYON 1 INGENIERIE
France
Address
43 Bd Du 11 Novembre 1918 - L'atrium
Villeurbanne
BIOMÉRIEUX SA
France
Address

Marcy L'etoile
UNIVERSITÉ CLAUDE BERNARD LYON 1
France
Address
43 Bd Du 11 Novembre 1918
Villeurbanne