Obiettivo BACKGROUND Visceral leishmaniasis (VL) is a neglected life-threatening vector-borne disease. More than 90% of the reported VL cases occur in the Indian subcontinent, where it is considered a problem of public health importance. Though a regional eliminat ion plan was launched in 2001, current approaches fail to control a VL epidemic in Bihar (India). Case-detection and treatment is the main strategy, with insecticide-spraying being applied to a variable extent. The efficacy of insecticide-treated bednets has been demonstrated so far in the prevention of cutaneous leishmaniasis, but not yet for VL.METHODS The efficacy of long-lasting impregnated bednets (LLIN) on VL prevention will be assessed in a community intervention trial in the Bihar focus, that e xtends on both sides of the Indian-Nepalese border. The study aims to demonstrate a 50% reduction in L.donovani incidence rates in the intervention group compared to control. Twenty clusters of households will be randomly allocated to the intervention or to the control arm. Complementary to the trial, technology assessment (TA) and socio-economic studies (SES) will be conducted. TA will evaluate the efficacy of competing technologies on a scale of proof-of-principle , as several formats of treated fabri cs are currently being proposed by industry. SES will evaluate the acceptability and cost-effectiveness of LLIN compared to alternative community-based vector-control methods by an appropriate mix of quantitative and qualitative methods. DISCUSSION The proposed study targets the poorest segments of society, aiming at poverty reduction in line with EU development aid policy. Research institutes from north and south will carry out the project in collaborative partnership , with specific targets for trai ning and capacity strengthening. The partnership will involve the local health policymakers and the community, as the goal is to integrate research results into disease control policy. Campo scientifico medical and health scienceshealth sciencespublic health Programma(i) FP6-INCO - Specific measures in support of international cooperation: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Argomento(i) INCO-2003-A1.3 b - Knowledge and technologies to improve control of neglected communicable diseases Invito a presentare proposte FP6-2003-INCO-DEV-2 Vedi altri progetti per questo bando Meccanismo di finanziamento IP - Integrated Project Coordinatore PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE Contributo UE Nessun dato Indirizzo Nationalestraat 155 ANTWERP Belgio Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (6) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto B.P. Koirala Institute of Health Sciences Nepal Contributo UE Nessun dato Indirizzo Ghopa DHARAN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Banaras Hindu University India Contributo UE Nessun dato Indirizzo BHU VARANASI Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato International Centre for Diarrhoeal Disease Research, Bangladesh Bangladesh Contributo UE Nessun dato Indirizzo 68 Shaheed Tajuddin Ahmed Sharani, Mohakhali DHAKA Mostra sulla mappa Costo totale Nessun dato London School of Hygiene and Tropical Medicine Regno Unito Contributo UE Nessun dato Indirizzo Keppel Street LONDON Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Rajendra Memorial Research Institute of Medical Sciences India Contributo UE Nessun dato Indirizzo Agamkuan PATNA,BIHAR Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Université de Genève Svizzera Contributo UE Nessun dato Indirizzo Rue du Général-Dufour 24 GENEVA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato
