Obiettivo Biochip technology allows assessing the expression of thousands of genes in parallel, opening the way to individualised healthcare. The INDIGO project will replace the current bulky and expensive technology used to hybridise and read fluorescent biochips by a lab-on-chip approach, with integrated signal processing and networking capacities. The project reconsiders the complete biochip user chain, and optimises each component in relation to others.At the core of INDIGO is an innovative, miniature and highly sensitive, yet disposable fluorescence-based biosensor. It replaces the usual glass slide supporting the biological reaction by a sandwich of chemical and optical layers monolithically grafted on a CMOS or CCD image sensor. Intermediate layers play an essential optical role for guiding and filtering light. The upper side of the sensor is devoted to biology, the lower side to imaging by direct, and efficient light collection by the pixels. Improving signal level will enhance the sensitivity and robustness of the biological measurements.Such a lensless imaging device produces images with new characteristics and needs development of new data processing software. The image produced by the sensor will be read in a laptop-connected readout head, and then filtered, segmented and measured; the results will be normalised, written in a standard format, ready to be recorded into a database or transmitted through networks.With its user-friendly interface, the system will undergo clinical validation in biology labs, on samples from patients with different cancers and cardiovascular diseases. The INDIGO project is well suited to the joint IST and NMP call on biosensors for Diagnosis and Healthcare. On the NMP side, smart and hybrid materials like sol-gels with extreme characteristics, able to be industrially coated, as thin layers will be developed. On the IST side, new data treatment chain will give standardised biological data usable by the medical community at large. Campo scientifico engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensorsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsignal processingmedical and health sciencesclinical medicinecardiologycardiovascular diseasesnatural sciencescomputer and information sciencesdata sciencedata processing Programma(i) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Argomento(i) Data not available Invito a presentare proposte Data not available Meccanismo di finanziamento STREP - Specific Targeted Research Project Coordinatore ATMEL-Grenoble SAS Contributo UE Nessun dato Indirizzo Avenue de Rochepleine 123 SAINT EGREVE Francia Mostra sulla mappa Costo totale Nessun dato Partecipanti (5) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS Francia Contributo UE Nessun dato Indirizzo 60, BOULEVARD SAINT-MICHEL PARIS Mostra sulla mappa Costo totale Nessun dato Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali Italia Contributo UE Nessun dato Indirizzo Via Benedetto Varchi, 59 FIRENZE Mostra sulla mappa Costo totale Nessun dato FUNDACIÓN VALENCIANA DE INVESTIGACIONES BIOMÉDICAS Spagna Contributo UE Nessun dato Indirizzo AVDA. AUTOPISTA DEL SALER, NÚM. 16 VALENCIA Mostra sulla mappa Costo totale Nessun dato Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III Spagna Contributo UE Nessun dato Indirizzo SINESIO DELGADO, 6 MADRID Mostra sulla mappa Costo totale Nessun dato GENEWAVE Francia Contributo UE Nessun dato Indirizzo 4 RUE PIERRE FONTAINE 91000 EVRY Mostra sulla mappa Costo totale Nessun dato