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Development of New Drugs for the Treatment of Malaria

Objetivo

Leading groups of malaria researchers will integrate their expertise in malaria biology and drug development to exploit new scientific and political opportunities to secure the development of a portfolio of viable novel AntiMalarial drugs. New chemical entities will be commercially attractive to industrial partners and through the generation of PPPs, will result in affordable new AntiMalarial drugs. The scientific programme comprises complementary clusters of basic and applied scientific investigation, building on the technology platforms generated by the BioMalPar NoE providing candidate molecules for evaluation by EDCTP.The IP will focus on: quinolines, peroxides, lipid targets, other targets and post candidate development. The project brings together European research of international reputation in the field of malaria biology and chemotherapy and their collaborators in malaria-endemic areas. Through AntiMal's programme of jointly executed research, 27 European research groups will support the network's goals to generate viable lead drug molecules in collaboration with 6 industrial partners (5 SMEs) and 4 partners from endemic countries (2 SMEs).These activities in strengthening existing European excellence will increase institutional integration and create a durable structure of basic and applied malaria research in Europe with a focus on drugs, and will establish critical mass at the European level and integrate malaria specialists into a "virtual drug discovery and development" structure with one focused scientific objective, the delivery of a new drug/s for malaria. We now propose to extend this consortium to iclude a further three African-based partners with exciting drug discovery/development initiatives. The first of these focuses on antifolate based antimalarials and the second on the generation of drugs from natural products. These additions to the programme will extend the Anitmal portfolio in areas underrepresented in the original IP.

Ámbito científico

Programa(s)

Tema(s)

Convocatoria de propuestas

FP6-2004-LIFESCIHEALTH-5
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Régimen de financiación

IP - Integrated Project

Coordinador

LIVERPOOL SCHOOL OF TROPICAL MEDICINE
Aportación de la UE
Sin datos
Dirección
Pembroke Place
LIVERPOOL
Reino Unido

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Coste total
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Última actualización: 20 Diciembre 2011

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Permalink: https://cordis.europa.eu/project/id/18834/es

European Union, 2024