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An innovative implantable device and management platform to prevent chronic fluid congestion

Project description

An implantable device for pathologic fluid removal

In congestive heart failure (CHF), the heart is unable to pump blood effectively, leading to pathologic fluid accumulation in the body. Oral medications are often ineffective, with hospitalisation and invasive treatments being the only option to remove excessive fluid. The EIC-funded FILBERT project has developed a unique implantable peritoneal ultrafiltration system for patients who show resistance to diuretics. The device gently drains extraneous fluids in the urinary system, preventing fluid buildup before it becomes critical. It also enables constant and remote monitoring by physicians, who can adjust treatment as needed. With millions of CHF patients suffering from pathologic fluid accumulation, FILBERT shifts fluid management from hospitals to home and promises to enhance patient quality of life.

Objective

Pathologic fluid overload is a main clinical complication of congestive heart failure (CHF). CHF is a severe chronic disease affecting ~28 M people worldwide. Around 8 M of CHF patients are resistant to oral medications and undergo frequent hospitalizations to remove extra fluids with aggressive acute treatments, all carrying severe complications. None of these treatments can prevent fluid accumulation. The Israeli SME Paragate Medical has developed FILBERT, a unique implantable peritoneal ultrafiltration system for diuretic resistant CHF patients. It enables 24/7 monitoring and gentle draining of extra fluids in the urinary system, preventing their accumulation. A remote treatment management platform allows physicians to continuously control patients conditions and timely adjust therapy to prevent fluid accumulation. FILBERT shifts the paradigm of fluid congestion care from the hospital to the home, improving patients quality of life and saving billions to healthcare systems.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance

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Call for proposal

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(opens in new window) HORIZON-EIC-2023-ACCELERATOR-01

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Coordinator

PARAGATE MEDICAL LTD
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 2 500 000,00
Address
13 WADI EL HADJ
Nazareth
Israel

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 3 994 993,75
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