Objective
In a human cell there are about 20k protein coding genes (genome) that originate ~100k proteins (proteome). Proteins are involved in complex networks of protein-protein interactions (PPIs) influenced by post-translational modifications (PTMs), the interactome of living cells (~800,000 entities). The genome is mostly static throughout cell lifetime and can be sequenced today in <1h. The proteome and interactome are changing with e.g. environment and health, and not yet fully known. Today's methods for proteomics and interactomics are tedious, and lack sensitivity, quantitativity and parallelism.
PICO-NGS combines ultra-high sensitivity (>10 fM) with high parallelism measuring proteins, PPIs, and PTMs simultaneously (>50 targets). This will disrupt the global proteomics market (29 B worth, 16% CAGR). This will fertilise ground-breaking academic research and accelerate developments in e.g. Pharma (drug discovery), Biotech (biomarkers/diagnosis), and Agrotech (crop sciences) industries.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomics
- agricultural sciencesagriculture, forestry, and fisheriesagriculture
- natural sciencesbiological sciencesgeneticsgenomes
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Keywords
Programme(s)
- HORIZON.3.1 - The European Innovation Council (EIC) Main Programme
Funding Scheme
HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended FinanceCoordinator
79110 Freiburg im Breisgau
Germany
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.