Pancreatic CAF-Derived Autotaxin Drives Autocrine CTGF Expression to Modulate Protumorigenic Signaling
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Autores:
Fanny Volat, Ragini Medhi, Lauren Z. Maggs, Marcel A. Deken, Alice Price, Lauren Andrews, Jonathan Clark, Diane Taylor, Alan Carruthers, Ewan Taylor-Smith, Natalia Pacheco, Simon A. Rudge, Amy Fraser, Andrea F. Lopez-Clavijo, Bebiana C. Sousa, Zoë Johnson, Giusy Di Conza, Lars van der Veen, Pritom Shah, Hilary Sandig, Hayley J. Sharpe, Stuart Farrow
Publicado en:
Molecular Cancer Therapeutics, Edición 24, 2025, ISSN 1535-7163
Editor:
American Association for Cancer Research (AACR)
DOI:
10.1158/1535-7163.MCT-23-0522
Cancer Research
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Autores:
Silvia Pietrobono; Fabio Sabbadini; Monica Bertolini; Domenico Mangiameli; Veronica De Vita; Federica Fazzini; Giulia Lunardi; Simona Casalino;
Publicado en:
Cancer Research, 2024, ISSN 0008-5472
Editor:
American Association for Cancer Research
DOI:
10.1158/0008-5472.CAN-23-0104
Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models
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Autores:
Matteo Centonze, Giusy Di Conza, Michael Lahn, Isabel Fabregat, Francesco Dituri, Isabella Gigante, Grazia Serino, Rosanna Scialpi, Livianna Carrieri, Roberto Negro, Elena Pizzuto & Gianluigi Giannelli
Publicado en:
Journal of Experimental & Clinical Cancer Research, 2023, ISSN 1756-9966
Editor:
BMC
DOI:
10.1186/s13046-023-02780-4
Characterization and translational development of IOA-289, a novel autotaxin inhibitor for the treatment of solid tumors
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Autores:
M.A. Deken K. Niewola-Staszkowska O. Peyruchaud N. Mikulčić M. Antolić P. Shah A. Cheasty A. Tagliavini A. Nizzardo M. Pergher L. Ziviani S. Milleri C. Pickering M. Lahn L. van der Veen G. Di Conza Z. Johnson
Publicado en:
IOTECH immuno-oncology and technology, 2023, ISSN 2590-0188
Editor:
ESMO
DOI:
10.1016/j.iotech.2023.100384
High levels of autotaxin and lysophosphatidic acid predict poor outcome in treatment of resectable gastric carcinoma
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Autores:
Annalisa Schirizzi, Rossella Donghia, Valentina De Nunzio, Natasha Renna, Matteo Centonze, Giampiero De Leonardis, Vincenza Lorusso, Alessia Fantasia, Sergio Coletta, Dolores Stabile, Annalisa Ferro, Maria Notarnicola, Angela D. Ricci, Claudio Lotesoriere, Michael Lahn, Rosalba D’Alessandro, Gianluigi Giannelli
Publicado en:
European Journal of Cancer, Edición 213, 2024, ISSN 0959-8049
Editor:
Elsevier BV
DOI:
10.1016/J.EJCA.2024.115066
