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Diagnosis of large vessel occlusion (LVO) in acute stroke for improving access to treatment

Project description

Portable diagnostic solution identifying acute stroke

Large vessel occlusion (LVO) is linked to an elevated risk of death and severe long-term disability. Stroke patients are commonly treated with mechanical thrombectomy, but require a cranial CT scan at a hospital first, resulting in a loss of precious time. The EU-funded LVOCheck project proposes a portable diagnostic solution to rapidly identify LVO in acute stroke patients, using just a drop of blood obtained through a fingerpick. This allows for swift triage in ambulances and direct transport to a thrombectomy centre, saving an average of 2 hours from symptom onset to treatment. This cost-effective innovation has the potential to revolutionise the triage and treatment of stroke patients, providing them better outcomes where they are asymptomatic or functionally independent.

Objective

LVOCheck is a portable diagnostic solution providing fast identification of large vessel occlusion (LVO) in acute stroke, just by analysing a blood drop from the patient's fingerpick. LVOCheck allows rapid triage of stroke patients already in the ambulance, so patients suffering a LVO can be directly driven to the closest thrombectomy centre to get the clot removed, without the need of a cranial CT scan at the nearest hospital. It avoids unnecessary patient transfers and waiting times, saving thereby an average of 2 hours from symptom onset to treatment. Our pilot studies have shown a clinical benefit of 15-20% more patients becoming asymptomatic or functionally independent.

LVOCheck is a cost-effective, worldwide scalable innovation that will transform the triage and treatment of stroke patients, lessening the enormous economic and social burden of stroke. The use of LVOCheck will dramatically shorten the time from stroke onset to therapy, reducing disability, and saving lives.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance

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Call for proposal

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(opens in new window) HORIZON-EIC-2022-ACCELERATOR-01

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Coordinator

ADVANCED BRAIN COMPANION DIAGNOSTICS SPAIN SL
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 2 772 276,00
Address
AVENIDA SAN FRANCISCO JAVIER 9 10 EDIFICIO SEVILLA
41018 Sevilla
Spain

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Sur Andalucía Sevilla
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 3 960 395,00
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