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The Holy Grail in Bone regeneration

Project description

Growing bones with a synthetic bone graft

Large bone defects are not easy to treat. Defects in the upper limb, which may be caused by trauma, tumour or infection, are particularly difficult. Funded by the European Innovation Council (EIC), the GreenBone project will develop a new acellular synthetic bone graft. By mimicking the chemical composition and 3D pore structure of natural human bone, GreenBone will provide an optimum microenvironment capable of driving inductive bone performance and de novo bone mineralisation response at the ectopic site. With the EIC Accelerator Grant, the project will introduce the first technologically advanced spinal implant. It combines the needed mechanical strength with enhanced regenerative capacity.

Objective

Regeneration of large bone defects is an unmet medical need with a high socio-economic burden, affecting millions of people worldwide. To overcome the limitations of existing solutions for bone replacement, we developed GreenBone, our pioneering acellular synthetic bone graft obtained from proprietary biomorphic transformation process of Rattan wood. By mimicking the chemical composition and 3D pore structure of natural human bone, we are able to provide an optimum microenvironment capable of driving inductive bone performance and de-novo bone mineralisation response at the ectopic site.
With the EIC accelerator grant first, we aim to disrupt the bone graft market by introducing the first technologically advanced spinal implant that combines the needed mechanical strength with enhanced regenerative capacity. We aim to bring our product to the spinal market segment in 2025, reaching 10% market share in 2030 and growing our company team to more than 40 skilled professionals.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-EIC-2021-ACCELERATOROPEN-01

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Coordinator

GREENBONE ORTHO SPA
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 2 458 128,75
Address
VIA ALBERT EINSTEIN 8
48018 Faenza Ra
Italy

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Est Emilia-Romagna Ravenna
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 3 511 612,50
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