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A unique commercially viable recombinant manufacturing platform for human fibrinogen (rhFib) & thrombin (rhThr

Obiettivo

We have developed the RECOFIB platform, a market first recombinant production platform for human fibrinogen (rhFib) & thrombin (rhThr). Using Chinese Hamster Ovary Cells (CHO) expression technology & patented upstream purification processes, we are the first producer of fully intact & functional recombinant fibrinogen and active thrombin at commercially acceptable cost ending reliance on blood plasma.

Our RECOFIB platform can produce individual fibrinogen variants whose specific functional properties can now be fully harnessed-a breakthrough discovery. From these individual variants, we can develop customized products for [1] bioactive topical hemostats to stop excessive bleeding during surgery; [2] medical implant coating reducing antibiotic resistance of MRSA bacterial biofilms and [3] supply of rhFib variants & rhThr as OEM products. Additional benefits of our rhFib variants compared to plasma fibrinogen include more stability, 10–100X higher purity, and improved safety profile.

Coordinatore

FIBRIANT BV
Contribution nette de l'UE
€ 2 500 000,00
Indirizzo
EMMY NOETHERWEG 2C
2333 BK LEIDEN
Paesi Bassi

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PMI

L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione.

Regione
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Collegamenti
Costo totale
€ 4 495 826,25