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Contenido archivado el 2024-05-29

Oxasilacyclohexenes -Chiral Scaffolds in Ruthenium Catalysed Tandem Synthesis

Objetivo

Oxasilacyclohexenes are synthetic intermediates with untapped potential; they combine the tuneable reactivity of substituted vinylsilanes with that of cyclic conformational rigidity. This proposal details the ruthenium catalysed formation of chiral oxasila cycle intermediates with pendant functionality capable of tandem reactions under residual Ru(II) Lewis acidic conditions. The first section focuses on the development of a research programme to optimise reactivity and selectivity in the synthesis of chiral oxasilacycle scaffolds and their ability to participate in tandem reactions. The second section will give examples of the application of this methodology in the synthesis of biologically interesting compounds.

Ámbito científico (EuroSciVoc)

Palabras clave

Tema(s)

Convocatoria de propuestas

FP6-2004-MOBILITY-6
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Régimen de financiación

OIF - Marie Curie actions-Outgoing International Fellowships

Coordinador

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Aportación de la UE
Sin datos
Dirección


Reino Unido
Coste total
Sin datos

Participantes (1)