Objetivo
This proposal will (further) develop and apply metagenomics tools to access the enzymatic potential borne in the cryptic biota of selected natural habitats, in particular target soil-related and aquatic ones. In the light of the environmental relevance of chitins and lignins (as natural compounds recalcitrant to degradation) and halogenated aliphatic and aromatic compounds (anthropogenic recalcitrant compounds), the enzymatic activities that we will target are functions able to degrade these compounds. A database of gene functions will be established and maintained. Next to its great relevance to environmental biotechnology including bioremediation, a spin-off of the work will be the discovery of novel biocatalytic functions of industrial relevance. We will in particular address the catabolic potential that is encoded by the mobilome, the collective pool of mobile genetic elements in the microbiota. We will further apply high-throughput (454-based) sequencing to rapidly unravel the metabolic complement in this mobile gene pool. The project brings together a suite of 15 contractors across Europe, encompassing 21 laboratories spread over 11 copuntries and including 4 SMEs. Most of the partners are renowned laboratories which have vast experience in metagenomics of environmental samples, biotechnology, enzymology, bioinformatics, the mobilome, waste management and bioremediation and enzyme production.
Ámbito científico
- natural sciencescomputer and information sciencesdatabases
- engineering and technologyenvironmental engineeringwaste management
- engineering and technologyenvironmental biotechnologybioremediation
- natural scienceschemical sciencesorganic chemistryaromatic compounds
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes
Palabras clave
Tema(s)
Convocatoria de propuestas
FP7-KBBE-2007-2A
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Régimen de financiación
CP-IP - Large-scale integrating projectCoordinador
9712CP Groningen
Países Bajos
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Participantes (17)
9712CP Groningen
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1165 Kobenhavn
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SE-141 89 Huddinge
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CV4 8UW COVENTRY
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6708 PB Wageningen
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69134 Ecully
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33615 Bielefeld
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06484 Quedlinburg
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3000 Leuven
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02044 VTT ESPOO
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1348 Louvain La Neuve
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21100 Varese
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1000 Ljubljana
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1900 La Plata
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1098 XH Amsterdam
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YO22 4PU Whitby
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75007 Paris
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