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Contenido archivado el 2024-06-18

Molecular and serological techniques to study Lassa virus ecology

Objetivo

Lassa fever is a zoonotic disease caused by Lassa virus. The disease is endemic in West Africa. Hemorrhagic courses of Lassa fever are associated with high mortality. It is estimated that 100,000 to 500,000 infections occur each year because of transmission of Lassa virus from its rodent reservoir (Mastomys natalensis) to human. Rodent control measures could reduce the risk of rodent-human transmission. However, the dynamics of virus-rodent interaction is poorly understood. This information is crucial to design efficient and cost-effective rodent control measures. Therefore, objective of the research project is to enhance knowledge on rodent ecology and molecular taxonomy as well as on microphylogeny, transmission, and persistence pattern of the virus in the rodent population. A second objective is the improvement of laboratory skills of the applicant in the area of virology and molecular biology to facilitate a multidisciplinary Lassa virus research linking rodent ecology, molecular epidemiology, diagnostics, and virology.

Convocatoria de propuestas

FP7-PEOPLE-IEF-2008
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Coordinador

BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN
Aportación de la UE
€ 230 288,97
Dirección
BERNHARD NOCHT STRASSE 74
20359 Hamburg
Alemania

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Región
Hamburg Hamburg Hamburg
Tipo de actividad
Research Organisations
Contacto administrativo
Stephan Günther (Prof.)
Enlaces
Coste total
Sin datos