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Priorities and Standards in Pharmacogenomic Research: Opportunities for a Safer and More Efficient Pharmacotherapy

Objective

Pharmacogenomics is the scientific discipline that relates inter-individual variation in drug response to genetic variation. While there have been major advances in basic genomic knowledge and genotyping technologies, translation into clinical practice has been slow. It is essential we quicken the pace of translational research in pharmacogenomics - at present, we cannot define which patients are going to respond to drugs, and which patients are going to develop adverse drug reactions. In this ITN, our concerted action across the EU, in cooperation with US researchers will train young investigators and clinicians (14 ESR and 2 ER) to establish, evaluate and retrieve relevant genetic information from patients, and relate it to clinical outcomes of drug therapy. This will be achieved through sharing patient materials, performing pooled analyses, transfer of knowledge and skills across laboratories and provide access to high-throughput technology platforms between 5 academic (3 EU, 1 ICPC, 1 OTC partners) and 4 industry partners (3 EU, 1AC partner). This will enhance translational research, promote uniform drug treatment standards throughout Europe and worldwide, and improve the competitiveness of the EU in this emerging and exciting field.

Field of science

  • /medical and health sciences/basic medicine/pharmacology and pharmacy/adverse drug reactions

Call for proposal

FP7-PEOPLE-ITN-2008
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH
Address
Auerbachstrasse 112
70376 Stuttgart
Germany
Activity type
Research Organisations
EU contribution
€ 1 270 261
Administrative Contact
Hiltrud Brauch (Prof.)

Participants (6)

EBERHARD KARLS UNIVERSITAET TUEBINGEN

Participation ended

Germany
Address
Geschwister-scholl-platz
72074 Tuebingen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Hiltrud Brauch (Prof.)
THE UNIVERSITY OF LIVERPOOL
United Kingdom
EU contribution
€ 1 051 440
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Karin Alecock (Ms.)
UNIVERZA V LJUBLJANI
Slovenia
EU contribution
€ 401 335
Address
Kongresni Trg 12
1000 Ljubljana
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Damjana Rozman (Prof.)
N.N. Petrov Institute of Oncology
Russia
EU contribution
€ 241 054
Address
Pesochny-2, Leningradskaya Str. 68
197758 St.-petersburg
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Evgeny Imyanitov (Prof.)
LAB 21 LIMITED
United Kingdom
EU contribution
€ 223 660
Address
Cambridge Science Park 184
CB4 0GA Cambridge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Berwyn Clarke (Dr.)
Delphic Diagnostics Ltd

Participation ended

United Kingdom
Address
Albemarle Street 26A
W1S 4HY London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
David John Back (Prof.)