Objective Despite significant effort over the past decade to design and implement new vaccines strategies against HIV, no one has met its promise to prevent infection and/or to reduce viral load until reaching eradication of the HIV reservoir. To reach this goal, a translational research is critical to propose innovative approaches for an HIV vaccine enhancing broadly cross-reactive mucosal, humoral and cellular immune responses specific to HIV antigens. Composed by 13 partners from 5 European countries and 2 International Cooperation countries, the CUT’HIVAC consortium gathers knowledge’s and cutting-edge technologies in vaccinology and HIV diseases to raise the challenge of developing a new HIV strategy. The CUT’HIVAC approach is based on innovative transcutaneous and/or mucosal needle-free vaccination methods in a perspective that new vaccine candidates will redirect immune response toward cytotoxic CD8 and mucosal humoral responses. The trust of the project derives from the proof-of-concept that combination of routes of immunization and delivery systems will shape the immune responses towards its protective arms against HIV. Clinical trials will be implemented with last cutting-edge generation of HIV DNA-GTU® candidate applied by transcutaneous, intradermal routes and/or mucosal administration of HIV-envelop protein-based vaccine. Large efforts will be positioned on the new genetic design of HIV antigens and delivery systems for developed and developing countries. These new vaccines will be tested in innovative preclinical approaches with a special highlight on routes of vaccination that will be translated into 2nd round of clinical trials in a perspective that could help to prevent and eradicate HIV. Through its integrative and multidisciplinary approach, CUT’HIVAC will therefore provide the basis for a novel approach in vaccination with a view to wide its application to other infectious diseases such as malaria and tuberculosis. Fields of science medical and health scienceshealth sciencesinfectious diseasesmalariamedical and health sciencesbasic medicineimmunologyimmunisationmedical and health scienceshealth sciencesinfectious diseasesRNA virusesHIVmedical and health sciencesclinical medicinepneumologytuberculosismedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH-2009-2.3.2-4 - Mucosal and topical vaccines for poverty-related diseases (HIV/AIDS, malaria and/or TB) Call for proposal FP7-HEALTH-2009-single-stage See other projects for this call Funding Scheme CP-IP - Large-scale integrating project Coordinator UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 Address Place jussieu 4 75252 Paris France See on map Activity type Higher or Secondary Education Establishments Administrative Contact Lucie Salvaudon (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 1 963 463,30 Participants (17) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITAET REGENSBURG Germany EU contribution € 1 270 801,00 Address Universitatsstrasse 31 93053 Regensburg See on map Region Bayern Oberpfalz Regensburg, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Christian Blomeyer (Dr.) Links Contact the organisation Opens in new window Website Opens in new window FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA Spain EU contribution € 974 680,00 Address Carretera de canyet 08916 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Administrative Contact Anna Tor (Ms.) Links Contact the organisation Opens in new window Website Opens in new window FIT BIOTECH OY Finland EU contribution € 1 648 460,00 Address Biokatu 8 33520 Tampere See on map Region Manner-Suomi Länsi-Suomi Pirkanmaa Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Liisa Irmeli Laitinen (Ms.) Links Contact the organisation Opens in new window Website Opens in new window CHARITE - UNIVERSITAETSMEDIZIN BERLIN Germany EU contribution € 621 400,00 Address Chariteplatz 1 10117 Berlin See on map Region Berlin Berlin Berlin Activity type Higher or Secondary Education Establishments Administrative Contact Eveline Fräßdorf (Ms.) Links Contact the organisation Opens in new window Website Opens in new window ST GEORGE'S HOSPITAL MEDICAL SCHOOL Participation ended United Kingdom EU contribution € 119 326,50 Address Cranmer terrace SW17 0RE London See on map Region London Inner London — West Wandsworth Activity type Higher or Secondary Education Establishments Administrative Contact Paul Craven (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Investigaciones Medicas en Salud Participation ended Peru EU contribution € 130 899,74 Address Jose de la torre ugarte 166 L 14 Lima See on map Activity type Research Organisations Administrative Contact Sergio Chavez (Mr.) Links Contact the organisation Opens in new window Website Opens in new window CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 759 760,00 Address Rue michel ange 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Sandrine Magnetto (Dr.) Links Contact the organisation Opens in new window Website Opens in new window MEDICAL RESEARCH COUNCIL United Kingdom EU contribution € 108 095,64 Address 20 park crescent W1B 1AL London See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Richard Frost (Mr.) Links Contact the organisation Opens in new window Website Opens in new window INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 96 811,04 Address Rue de tolbiac 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Mihaja Auguste (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Instituto Nacional de Saúde Mozambique EU contribution € 241 334,00 Address Avenida eduardo mondlane 1008 Maputo See on map Activity type Research Organisations Administrative Contact Maria Helena Abdul (Ms.) Links Contact the organisation Opens in new window NOVAMEN SAS Participation ended France EU contribution € 368 306,00 Address Rue de la république 69 69002 Lyon See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Vincent Grosbois (Mr.) Links Contact the organisation Opens in new window ACIES Consulting Group SAS France EU contribution € 0,00 Address Rue de la république 69 69002 Lyon See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Vincent Grosbois (Mr.) Links Contact the organisation Opens in new window Website Opens in new window GENEART AG Germany EU contribution € 109 599,00 Address Josef-engert-strasse 11 93053 Regensburg See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Melanie Meyer (Ms.) Links Contact the organisation Opens in new window Website Opens in new window ASOCIACION CIVIL IMPACTA SALUD Y EDUCACION Peru EU contribution € 282 338,00 Address Avenida almirante miguel grau 1010 L04 Lima See on map Activity type Research Organisations Administrative Contact Jose Joaquin Ojeda Celi (Mr.) Links Contact the organisation Opens in new window Website Opens in new window IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE United Kingdom EU contribution € 2 963 186,32 Address South kensington campus exhibition road SW7 2AZ London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Administrative Contact Tatjana Palalic (Ms.) Links Contact the organisation Opens in new window Website Opens in new window OBJECTIF RECHERCHE VACCIN SIDA France EU contribution € 30 966,60 Address Boulevard de l hopital 47-83 75013 Paris See on map Activity type Research Organisations Administrative Contact François Lecardonnel (Mr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITY COLLEGE LONDON United Kingdom EU contribution € 239 822,86 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Administrative Contact Malgorzata Kielbasa (Ms.) Links Contact the organisation Opens in new window Website Opens in new window
