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Prevention of Hospital Infections by Intervention and Training

Objective

The aim of PROHIBIT is to understand existing guidelines and practices to prevent healthcare associated infections (HAI) in European hospitals, identify factors that enable and prevent compliance with best practices, and test the effectiveness of interventions of known efficacy. The project will employ a mixed-methods approach combining the strengths of qualitative research, survey methods, observational and experimental designs. First, we will systematically review current guidelines on prevention of the most common HAIs within the EU, as well as schemes for surveillance and public reporting. Next, we will conduct a large-scale survey of what is actually being done in European hospitals, determining factors, and how these relate to bloodstream infection rates. The project will then focus on catheter-related bloodstream infection (CRBSI), a highly transmissible and reliably measured HAI, in a selected sample of European hospitals. In-depth interviews of healthcare staff and direct observation will be used to measure compliance with key prevention practices. A randomized effectiveness trial using a stepped wedge design will be conducted in intensive care units to determine the uptake and impact of 2 interventions (WHO hand hygiene protocol and so-called catheter bundle) on CRBSI as well as clinical and utilization outcomes. The information will be synthesized to develop recommendations for the EU, policy makers, managers and medical professionals to prevent HAI. Dissemination will include instructional workshops and on-line training materials.

Field of science

  • /medical and health sciences/clinical medicine/critical care medicine

Call for proposal

FP7-HEALTH-2009-single-stage
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

UNIVERSITE DE GENEVE
Address
Rue Du General Dufour 24
1211 Geneve
Switzerland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 883 041,98
Administrative Contact
Didier Pittet (Prof.)

Participants (8)

RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU
Netherlands
EU contribution
€ 985 908,56
Address
Antonie Van Leeuwenhoeklaan 9
3721 MA Bilthoven
Activity type
Research Organisations
Administrative Contact
Hajo Grundmann (Prof.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 505 488
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Petra Gastmeier (Prof.)
UNIVERSITAETSKLINIKUM FREIBURG
Germany
EU contribution
€ 360 600
Address
Hugstetter Strasse 49
79106 Freiburg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Gerhard Henninger (Mr.)
CENTRE HOSPITALIER REGIONAL DE MARSEILLE ASSISTANCE PUBLIQUE-HOPITAUX MARSEILLE
France
EU contribution
€ 4 800
Address
Rue Brochier 80
13354 Marseille Cedex 20
Activity type
Research Organisations
Administrative Contact
Hervé Richet (Prof.)
ORSZAGOS EPIDEMIOLOGIAI KOZPONT
Hungary
EU contribution
€ 25 800
Address
Albert Florian Utca 2-6
1097 Budapest
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Emese Szilágyi (Dr.)
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 143 425,46
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mike Robinson (Mr.)
WORLD HEALTH ORGANIZATION
Switzerland
EU contribution
€ 44 550
Address
Avenue Appia 20
1211 Geneve
Activity type
Research Organisations
Administrative Contact
Benedetta Allegranzi (Dr.)
Jagiellonian University in Krakow
Poland
EU contribution
€ 46 320
Address
Ul. Golebia 24
31007 Krakow
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jolanta Palowska (Ms.)