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PREvention of Late Stent Thrombosis by an Interdisciplinary Global European effort

Objectif

According to the European Society of Cardiology there has been an increase in the life expectancy at the age of 65 of the European population from 15.0 to 17.0 years in the years since 1980. In the elderly, up to 50% of deaths are caused by cardiovascular diseases, the majority accounted for by coronary artery disease. The most effective treatment for obstructive coronary disease is percutaneous intervention with coronary stenting and fuelled by the increasing disease burden there has been a rapid increase in the number of percutaneous coronary intervention procedures in Europe from 184,000 in 1992 to 885,000 in 2004. If the rate of progression remains constant, the projected number of coronary intervention procedures per annum will be about 1.5 million by 2010, with a stenting rate of close to 100%. The principal safety issue with current coronary stenting procedures is late stent thrombosis which, with a case mortality rate approaching 50%, makes this problem a very significant European health issue.
The PRESTIGE project will result in significant improvement in prediction and prevention of late stent thrombosis by providing novel strategies that causally impede incident events without increasing the overall risk of bleeding. These goals will be achieved by a multidisciplinary consortium formed by world-leading EU-based specialists covering the requisite scientific skills and experience.
Since the first drug-eluting stent was introduced in 2002 the growth of this sector has been explosive. Forecasts predicted the potential for this market segment to exceed €4.6 billion by 2009. The economic impact of this very ambitious project will be to provide the European health industries with novel stent products and new imaging technologies to identify patients at-risk, as well as amended European treatment guidelines. The social impact will be, amongst others, a tremendous cost reduction for the public and private health insurance systems all over Europe.

Appel à propositions

FP7-HEALTH-2010-single-stage
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Coordinateur

DEUTSCHES HERZZENTRUM MUNCHEN
Adresse
Lazarettstrasse 36
80636 Munich
Allemagne
Type d’activité
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Contribution de l’UE
€ 1 182 400
Contact administratif
Per Larsen (Mr.)

Participants (14)

AZIENDA OSPEDALIERA PAPA GIOVANNI XXIII
Italie
Contribution de l’UE
€ 454 210
Adresse
Piazza Oms 1
24127 Bergamo
Type d’activité
Other
Contact administratif
Giulio Guagliumi (Dr.)
SAMODZIELNY PUBLICZNY ZAKLAD OPIEKI ZDROWOTNEJ SZPITAL UNIWERSYTECKI W KRAKOWIE
Pologne
Contribution de l’UE
€ 58 200
Adresse
Ul. Kopernika 36
31 501 Krakow
Type d’activité
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Contact administratif
Dariusz Dudek (Prof.)
STICHTING SINT ANTONIUS ZIEKENHUIS
Pays-Bas
Contribution de l’UE
€ 371 620
Adresse
Koekoekslaan 1
3435 CM Nieuwegein
Type d’activité
Research Organisations
Contact administratif
Jurrien Maria Ten Berg (Dr.)
UNIVERSITY OF LEICESTER
United Kingdom
Contribution de l’UE
€ 669 364
Adresse
University Road
LE1 7RH Leicester
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Bikramjeet Singh (Mr.)
BENEDIKT-KREUTZ REHABILITATIONSZENTRUM FUER HERZ- UND KREISLAUFKRANKE BAD KROZINGEN EV

Participation terminée

Allemagne
Contribution de l’UE
€ 121 200
Adresse
Suedring 15
79189 Bad Krozingen
Type d’activité
Research Organisations
Contact administratif
Christian Valina (Dr.)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Contribution de l’UE
€ 990 356
Adresse
Rue De Tolbiac 101
75654 Paris
Type d’activité
Research Organisations
Contact administratif
Dina Falkenreck (Ms.)
RIGAS TEHNISKA UNIVERSITATE
Lettonie
Contribution de l’UE
€ 100 755
Adresse
Kalku Iela 1
1658 Riga
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Garry Kerch (Dr.)
KITOZYME SA
Belgique
Contribution de l’UE
€ 110 400
Adresse
Rue Haute Claire Parc Industriel 4
4040 Herstal
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Marie Hobe (Ms.)
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Allemagne
Contribution de l’UE
€ 346 466,50
Adresse
Ingolstadter Landstrasse 1
85764 Neuherberg
Type d’activité
Research Organisations
Contact administratif
Juergen Ertel (Dr.)
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgique
Contribution de l’UE
€ 711 270
Adresse
Oude Markt 13
3000 Leuven
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Walter Desmet (Prof.)
SERVICIO MADRILENO DE SALUD
Espagne
Contribution de l’UE
€ 121 440
Adresse
Plaza Carlos Trias Bertran 7
28020 Madrid
Type d’activité
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Contact administratif
Fernando Alfonso (Dr.)
BIOTRONIK SE & CO. KG
Allemagne
Contribution de l’UE
€ 380 980
Adresse
Woermannkehre 1
12359 Berlin
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Alexander Rzany (Dr.)
NEOPLAS GMBH
Allemagne
Contribution de l’UE
€ 360 980
Adresse
Walther Rathenau Strasse 49A
17489 Greifswald
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Renate Schönebeck (Ms.)
UNIVERSITATS-HERZZENTRUM FREIBURG-BAD KROZINGEN GMBH
Allemagne
Adresse
Sudring 15
79189 Bad Krozingen
Type d’activité
Research Organisations
Contact administratif
Gerhard Henninger (Mr.)