Objectif The aim is to integrate photosynthetic solar energy conversion and synthesis of volatile engine-ready transport fuel in a single photobiological process. The focus is placed on the construction of phototrophic model systems for synthesis of the short-chain alkane propane (C3H8). Propane can be used in existing engines without further chemical conversion and can be easily recovered from the production process without destructive harvesting and extraction. However, no commercial biological production process exists and there is no known metabolic pathway for short-chain alkane biosynthesis. The intention is to construct a synthetic pathway for propane biosynthesis. In order to facilitate the construction, alkane biosynthetic pathways are studied in detail and genes encoding key-enzymes are isolated from diverse organisms.In order to directly capture solar energy to drive fuel biosynthesis, the synthetic pathways are assembled in the photosynthetic model organism Synechocystis sp. PCC 6803. Native host metabolism is thereafter optimized to maximize the delivery of metabolic precursors and reducing energy to the synthetic pathways. In order to facilitate strain construction, cyanobacterial host strains are optimized for metabolic engineering and hydrocarbon fuel biosynthesis.The project has the ultimate aim to generate cyanobacteria strains that synthesize short-chain alkane using only light, CO2 and H2O as substrate. The project has a clear applied target with high potential for socio-economical impact and a high risk / high gain character. Champ scientifique engineering and technologyenvironmental engineeringenergy and fuelsrenewable energysolar energyengineering and technologyindustrial biotechnologymetabolic engineeringnatural scienceschemical sciencesorganic chemistryhydrocarbonsnatural scienceschemical sciencesorganic chemistryaliphatic compoundsengineering and technologyenvironmental engineeringenergy and fuelsenergy conversion Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) ERC-SG-LS9 - ERC Starting Grant - Applied life sciences and biotechnology Appel à propositions ERC-2010-StG_20091118 Voir d’autres projets de cet appel Régime de financement ERC-SG - ERC Starting Grant Institution d’accueil IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Contribution de l’UE € 334 188,60 Adresse SOUTH KENSINGTON CAMPUS EXHIBITION ROAD SW7 2AZ LONDON Royaume-Uni Voir sur la carte Région London Inner London — West Westminster Type d’activité Higher or Secondary Education Establishments Chercheur principal Patrik Raymond Jones (Dr.) Contact administratif Brooke Alasya (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Bénéficiaires (2) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Royaume-Uni Contribution de l’UE € 334 188,60 Adresse SOUTH KENSINGTON CAMPUS EXHIBITION ROAD SW7 2AZ LONDON Voir sur la carte Région London Inner London — West Westminster Type d’activité Higher or Secondary Education Establishments Chercheur principal Patrik Raymond Jones (Dr.) Contact administratif Brooke Alasya (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée TURUN YLIOPISTO Participation terminée Finlande Contribution de l’UE € 581 931,30 Adresse YLIOPISTONMAKI 20014 Turku Voir sur la carte Région Manner-Suomi Etelä-Suomi Varsinais-Suomi Type d’activité Higher or Secondary Education Establishments Contact administratif Mari Riipinen (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
