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Targeting Hernia Operation Using Sustainable Resources and Green Nanotechnologies. An Integrated Pan-European Approach

Objective

Hernia operations are among the most common surgical procedures performed today with over 20 million cases annually worldwide. Hernia incidents are associated with pain and poor quality-of-life for the patient and lead to enormous healthcare costs, exceeding US $48 billion in the US annually. At present, hernia operations rely heavily on non-degradable polypropylene, polytetrafluoroethylene and nylon meshes. However, these polymers are often associated with foreign body reaction; implant failure; and hernia reoccurrence (over 42%). Moreover, leaking chemicals of these polymers are often deleterious to the surrounding cells and tissue and immobilise post-operative drug treatments. In addition, the process technologies are often associated with environmental risks. Herein, we propose a novel approach that employs recent advances in green nanotechnology and sustainable raw materials for scaffold fabrication that not only will eliminate toxic chemicals from the processes, but will also enhance functional repair due to superior biological properties. Specifically, we aim to fabricate a nano-fibrous mesh with well-defined nano-topography using cellulose; human recombinant collagen, derived from transgenic tobacco plants; and biodegradable polylactic/polyglycolic acid as raw materials. The green credentials of this innovative approach lie in the use of sustainable eco-friendly raw materials that will produce biodegradable waste products and therefore replacing hazardous chemicals currently in use. Thus, this proposal directly fits the call for the substitution of materials or components with ‘green nano-technology’.

Call for proposal

FP7-NMP-2010-SMALL-4
See other projects for this call

Coordinator

NATIONAL UNIVERSITY OF IRELAND GALWAY
Address
University Road
H91 Galway
Ireland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 561 600
Administrative Contact
Mari Vahey (Ms.)

Participants (10)

THE HEBREW UNIVERSITY OF JERUSALEM
Israel
EU contribution
€ 290 886
Address
Edmond J Safra Campus Givat Ram
91904 Jerusalem
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jane Turner (Ms.)
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 223 481
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
Eusebio Jiménez Arroyo (Mr.)
AARHUS UNIVERSITET
Denmark
EU contribution
€ 177 770
Address
Nordre Ringgade 1
8000 Aarhus C
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Lene Birksø Bødskov (Ms.)
CollPlant Ltd.
Israel
EU contribution
€ 275 740
Address
Sapir Street, Weizmann Science Park 3
74140 Ness Ziona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Adi Rittner Ben-Tzion (Mr.)
LUXILON INDUSTRIES NV
Belgium
EU contribution
€ 234 500
Address
Vosveld 11
2110 Wijnegem
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Rolf Ribbens (Mr.)
CENTRE SCIENTIFIQUE & TECHNIQUE DEL'INDUSTRIE TEXTILE BELGE ASBL
Belgium
EU contribution
€ 220 850
Address
Rue Montoyer 24/2
1000 Bruxelles
Activity type
Research Organisations
Administrative Contact
Luc Ruys (Dr.)
PROXY BIOMEDICAL LIMITED
Ireland
EU contribution
€ 214 620
Address
Coilleach Spiddal
H91 Galway
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Shaun Donnellan (Mr.)
ASHLAND SPECIALTIES IRELAND LIMITED
Ireland
EU contribution
€ 264 400
Address
National Science Park, Building V, Dublin Road, Petitswood
N91 F6PD Mullingar, Westmeath
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Colm O'dowd (Mr.)
NAMSA
France
EU contribution
€ 147 075
Address
Chemin De L Islon 115
38670 Chasse Sur Rhone
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Eleonore Puissant (Dr.)
EUROPEAN RESEARCH SERVICES GMBH
Germany
EU contribution
€ 81 744
Address
Roentgenstrasse 19
48149 Muenster
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Oliver Panzer (Mr.)