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Universal microarrays for the evaluation of fresh-water quality based on detection of pathogens and their toxins

Objective

Monitoring the quality of drinking water is of paramount importance for public health. “Water is not a commercial product but a heritage that must be protected, defended and treated as such” (Water Framework Directive 2000/60/EC). The threat of waterborne diseases in Europe will predictably increase in the future as the human population increases and as a result of globalization and migration from non-EU countries and of climate change. Development of efficient, sensitive, robust, rapid and inexpensive tests to monitor various aspects of water quality represents an essential milestone within the strategy for control and prevention of diseases caused by waterborne pathogens and by algal toxins. Traditional methods for the detection of waterborne pathogens, based on cultivation, biochemical characterisation and microscopic detection are laborious and time-consuming; molecular biological tools have now greatly enhanced our ability to investigate biodiversity by identifying species and to estimate gene flow and distribution of species in time and space. μAQUA aims to design and develop a universal microarray chip for the high-throughput detection in water of known and emerging pathogens (bacteria, viruses, protozoa and cyanobacteria) and to assess the water quality monitoring the presence of select bioindicators (i.e. diatoms). A chip able to detect cyanobacterial toxins will also be developed. These innovative molecular tools should be amenable to automation so that they could be deployed on moorings for routine semi-continuous monitoring of water quality. μAQUA also aims to identify cyanophages potentially capable of controlling and mitigating the periodical blooming of toxic cyanobacteria in drinking water reservoirs. Overall, these innovative and cost efficient technologies will reduce energy requirements and improve performance of water treatment, and allow rapid management response to new situations brought about by environmental (including climatic) changes.

Field of science

  • /social sciences/sociology/globalization
  • /medical and health sciences/health sciences/public and environmental health
  • /natural sciences/biological sciences/microbiology/virology
  • /natural sciences/earth and related environmental sciences/atmospheric sciences/climatology/climatic changes
  • /social sciences/sociology/industrial relations/automation
  • /natural sciences/biological sciences/microbiology/protozoology
  • /social sciences/sociology/social problems/migration

Call for proposal

FP7-KBBE-2010-4
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

UNIVERSITA DEGLI STUDI DI CAMERINO
Address
Piazza Cavour 19F
62032 Camerino
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 408 098
Administrative Contact
Ermanno Pieroni (Dr.)

Participants (11)

UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION
United Kingdom
EU contribution
€ 248 223
Address
Winston Churchill Avenue University House
PO1 2UP Portsmouth
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Elizabeth Bartle (Dr.)
UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6
France
EU contribution
€ 383 110
Address
Place Jussieu 4
75252 Paris
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Stéphanie Rossard (Dr.)
VEOLIA ENVIRONNEMENT RECHERCHE ET INNOVATION SNC
France
EU contribution
€ 107 413
Address
Chemin De La Digue
78600 Maisons Laffitte
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Michel Hurel (Mr.)
ISTITUTO SUPERIORE DI SANITA
Italy
EU contribution
€ 286 180
Address
Viale Regina Elena 299
00161 Roma
Activity type
Research Organisations
Administrative Contact
Rosa Maria Martoccia (Dr.)
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 344 115
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Donal Doolan (Mr.)
NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES
Bulgaria
EU contribution
€ 160 377
Address
Blvd. Yanko Sakazov 26
1504 Sofia
Activity type
Research Organisations
Administrative Contact
Hristo Taskov (Prof.)
THE QUEEN'S UNIVERSITY OF BELFAST
United Kingdom
EU contribution
€ 228 650
Address
University Road Lanyon Building
BT7 1NN Belfast
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Michael Daly (Mr.)
MariLim Gesellschaft fur Gewasseruntersuchung mbH
Germany
EU contribution
€ 144 264
Address
Heinrich Wohlk Strasse 14
24232 Schonkirchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thomas Meyer (Mr.)
ISTANBUL UNIVERSITESI
Turkey
EU contribution
€ 168 780
Address
Istanbul Universitesi Center Campus Beyazit Eminonu
34452 Istanbul
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Merİç Albay (Prof.)
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Spain
EU contribution
€ 161 697
Address
Colexio De San Xerome Praza Do Obradoiro S/n
15782 Santiago De Compostela
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Martin Cacheiro Martinez (Mr.)
SCIENION AG
Germany
EU contribution
€ 264 752
Address
Otto Hahn Strasse 15
44227 Dortmund
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Horst Muller (Mr.)