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Functional and structural analysis of the mammalian nonsense-mediated mRNA decay pathway

Publicaciones

The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1

Autores: Elisa Izaurralde; Stefanie Jonas; Chung-Te Chang; Belinda Loh; Natalia Bercovich
Publicado en: Oxford University Press Nucleic Acids Research 2014
Identificador permanente: PubMed Central ID:PMC4005699; PubMed ID:24510189; Digital Object Identifier:10.1093/nar/gku129

Structure and assembly of the NOT module of the human CCR4–NOT complex

Autores: Stefanie Jonas; Tobias Raisch; Lara Wohlbold; Duygu Kuzuoğlu-Öztürk; Ying Chen; Elisa Izaurralde; Andreas Boland; Oliver Weichenrieder
Publicado en: Springer Nature 2013
Identificador permanente: Digital Object Identifier:10.1038/nsmb.2681

An unusual arrangement of two 14-3-3-like domains in the SMG5–SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay

Autores: Stefanie Jonas; Oliver Weichenrieder; Elisa Izaurralde
Publicado en: Cold Spring Harbor Laboratory 2013
Identificador permanente: Digital Object Identifier:10.1101/gad.206672.112; PubMed Central ID:PMC3566313; PubMed ID:23348841

Structural basis for the Nanos-mediated recruitment of the CCR4–NOT complex and translational repression

Autores: Stefanie Jonas; Elisa Izaurralde; Tobias Raisch; Dipankar Bhandari; Oliver Weichenrieder
Publicado en: Cold Spring Harbor Laboratory 2014
Identificador permanente: PubMed Central ID:PMC4003280; PubMed ID:24736845; Digital Object Identifier:10.1101/gad.237289.113

The role of disordered protein regions in the assembly of decapping complexes and RNP granules

Autores: Elisa Izaurralde; Stefanie Jonas
Publicado en: Cold Spring Harbor Laboratory Press 2013
Identificador permanente: PubMed Central ID:PMC3877753; PubMed ID:24352420; Digital Object Identifier:10.1101/gad.227843.113

The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2.

Autores: Belinda Loh; Stefanie Jonas; Elisa Izaurralde
Publicado en: Cold Spring Harbor Laboratory Press 2013
Identificador permanente: PubMed Central ID:PMC3850096; PubMed ID:24115769; Digital Object Identifier:10.1101/gad.226951.113