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Preserving old antibiotics for the future : assessment of clinical efficacy by a pharmacokinetic/pharmacodynamic approach to optimize effectiveness and reduce resistance for off-patent antibiotics


Use of old antibiotics now and in the future from a pharmacokinetic/pharmacodynamic perspective

Autori: Anouk E. Muller; Johan W. Mouton; Ursula Theuretzbacher
ID permanente: Handle:2066/152910; PubMed ID:26093075; Digital Object Identifier:10.1016/j.cmi.2015.06.007

Intrathecal or intraventricular therapy for post-neurosurgical Gram-negative meningitis: matched cohort study

Autori: Mical Paul; Z. H. Rappaport; Ben Shofty; Menashe Zaaroor; Menashe Zaaroor; T. Binawi; Gill E. Sviri; Gill E. Sviri; Ami Neuberger; Ami Neuberger; T. Babitch; M. E. Naffaa; M. E. Naffaa
Pubblicato in: Elsevier BV 2015
ID permanente: Digital Object Identifier:10.1016/j.cmi.2015.09.023; PubMed ID:26456474

Inter occasion variability in individual optimal design

Autori: Anders N. Kristoffersson; Lena E. Friberg; Joakim Nyberg
Pubblicato in: Springer Science and Business Media LLC Journal of Pharmacokinetics and Pharmacodynamics 2015
ID permanente: Digital Object Identifier:10.1007/s10928-015-9449-6; PubMed ID:26452548; PubMed Central ID:PMC4624834

Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol

Autori: Dafna Yahav; Dafna Yahav; Rixt A. Wijma; Giusi Cavezza; Amir Nutman; Amir Nutman; Mical Paul; Mical Paul; Anastasia Antoniadou; Yehuda Carmeli; Anders N. Kristoffersson; George L. Daikos; Yaakov Dickstein; Leonard Leibovici; Leonard Leibovici; Noa Eliakim-Raz; Noa Eliakim-Raz; Yael Dishon Benattar; Johan W. Mouton; Roberto Andini; Amos Adler; Oren Zusman; Oren Zusman; Ursula Theuretzbacher; Inbar Levi; Lena E. Friberg; Fidi Koppel; Anna Skiada; Emanuele Durante-Mangoni; Sergey Altunin
ID permanente: PubMed ID:27098822; PubMed Central ID:PMC4838684; Handle:2066/171002; Digital Object Identifier:10.1136/bmjopen-2015-009956; Handle:1765/119948

Rectal Swabs Are Suitable for Quantifying the Carriage Load of KPC-Producing Carbapenem-Resistant Enterobacteriaceae

Autori: A. Lerner; Shiri Navon-Venezia; Inna Chmelnitsky; J. Romano; Yehuda Carmeli; Rotem Edgar
ID permanente: PubMed ID:23295937; PubMed Central ID:PMC3591867; Digital Object Identifier:10.1128/aac.01275-12

Comparative Genomics of Community-Associated Methicillin-Resistant Staphylococcus aureus Shows the Emergence of Clone ST8-USA300 in Geneva, Switzerland

Autori: Jacques Schrenzel; Elodie von Dach; Patrice Francois; Stéphan Juergen Harbarth; Seydina M. Diene; Carolina Fankhauser
ID permanente: Digital Object Identifier:10.1093/infdis/jiv489

Decolonization of intestinal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae with oral colistin and neomycin: a randomized, double-blind, placebo-controlled trial

Autori: Jacques Schrenzel; Benedikt Huttner; Ilker Uçkay; Danièle Schaerrer; Didier Pittet; Americo Agostinho; Antoine Andremont; Andrew J. Stewardson; Stéphan Juergen Harbarth; Thomas Haustein; Gesuele Renzi
ID permanente: PubMed ID:23719234; Digital Object Identifier:10.1093/jac/dkt174