Objective
The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and diabetes due to last years re-discovery of functional BAT in adult humans by several of the members of the DIABAT network (van Marken LIchtenbelt et al., N. Engl. J. Med. 360, 1500, 2009; Virtanen…, Enerbäck & Nuutila, N. Engl. J. Med. 360, 1518, 2009) along with sharp rise in insight in cellular, genetic, and regulatory mechanisms from animal studies. Therefore, the DIABAT project aims at recruiting and re-activating endogenous energy-dissipating BAT as a preventive and/or remedial measure for weight and blood sugar control in obesity-related type 2 diabetes (“diabesity”), thereby halting or preventing destruction and facilitating recovery of pancreatic beta-cells under diabetic conditions.
Fields of science
Not validated
Not validated
Call for proposal
FP7-HEALTH-2011-two-stage
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Funding Scheme
CP-FP - Small or medium-scale focused research projectCoordinator
69120 Heidelberg
Germany
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Participants (20)
142 20 Praha 4
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2100 Copenhagen Ø
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75794 Paris
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8010 Graz
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Participation ended
SW7 2AZ LONDON
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6200 MD Maastricht
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6229 ER Maastricht
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51429 Bergish Gladbach
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10691 Stockholm
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80333 Muenchen
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60121 Ancona
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07122 Palma De Mallorca
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1165 Kobenhavn
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1211 Geneve
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405 30 Goeteborg
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20014 Turku
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75654 Paris
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8092 Zuerich
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1015 LAUSANNE
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CV4 8UW COVENTRY
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