Ziel
The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and diabetes due to last years re-discovery of functional BAT in adult humans by several of the members of the DIABAT network (van Marken LIchtenbelt et al., N. Engl. J. Med. 360, 1500, 2009; Virtanen…, Enerbäck & Nuutila, N. Engl. J. Med. 360, 1518, 2009) along with sharp rise in insight in cellular, genetic, and regulatory mechanisms from animal studies. Therefore, the DIABAT project aims at recruiting and re-activating endogenous energy-dissipating BAT as a preventive and/or remedial measure for weight and blood sugar control in obesity-related type 2 diabetes (“diabesity”), thereby halting or preventing destruction and facilitating recovery of pancreatic beta-cells under diabetic conditions.
Wissenschaftliches Gebiet
Programm/Programme
Thema/Themen
Aufforderung zur Vorschlagseinreichung
FP7-HEALTH-2011-two-stage
Andere Projekte für diesen Aufruf anzeigen
Finanzierungsplan
CP-FP - Small or medium-scale focused research project











Koordinator
69120 Heidelberg
Deutschland
Beteiligte (20)
142 20 Praha 4
2100 Copenhagen Ø
75794 Paris
8010 Graz
Beteiligung beendet
SW7 2AZ London
6200 MD Maastricht
6229 ER Maastricht
51429 Bergish Gladbach
10691 Stockholm
80333 Muenchen
60121 Ancona
07122 Palma De Mallorca
1165 Kobenhavn
1211 Geneve
405 30 Goeteborg
20014 Turku
75654 Paris
8092 Zuerich
1015 Lausanne
CV4 8UW Coventry